Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MLNR | O43193 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12319847 | 0.85 | PDK2 (0.37) | PDK2PDK1PDK3PDK4MAPT | |
| SCHEMBL20751938 | 0.83 | PDK2 (0.35) | PDK2PDK1PDK3PDK4ESR1 | |
| SCHEMBL23040346 | 0.82 | GAA (0.42) | PDK2ESR1ESR2EGFRMAPT | |
| SCHEMBL23193115 | 0.82 | KDM1A (0.36) | PDK2EGFRMLNRNR1I2CHRM2 | |
| SCHEMBL30827116 | 0.80 | PDK2 (0.36) | PDK2MAPTRAB9AL3MBTL1 | |
| SCHEMBL26900008 | 0.78 | PTGER4 (0.39) | PDK2EGFRMAPTMAPK1RAB9A | |
| SCHEMBL10044314 | 0.77 | GAA (0.42) | PDK2ESR1ESR2EGFRMAPT | |
| SCHEMBL26952461 | 0.75 | ESR1 (0.42) | PDK2ESR1ESR2EGFRMAPT | |
| SCHEMBL26530733 | 0.75 | PDK2 (0.33) | PDK2PDK1PDK3PDK4EGFR | |
| SCHEMBL23040350 | 0.74 | PDK2 (0.36) | PDK2MAPTRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017774-B2 | Producing method for iridium complex | CANON KABUSHIKI KAISHA (JP) | 2011-09-13 | — | — | US | disclosed |
| US-20070232803-A1 | PRODUCING METHOD FOR IRIDIUM COMPLEX | CANON KABUSHIKI KAISHA (JP) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232803-A1 | PRODUCING METHOD FOR IRIDIUM COMPLEX | LAGE3, EML4, INTS9 | PDK2 1596/4885PDK1 715/4885PDK3 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.