Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12320178 | 0.91 | IDO1 (0.51) | IDO1PIN1FFAR1SLC6A4PDPK1 | |
| SCHEMBL12320500 | 0.85 | IDO1 (0.45) | IDO1PIN1FFAR1SLC6A4PDPK1 | |
| SCHEMBL1746749 | 0.80 | IDO1 (0.49) | IDO1PIN1FFAR1SLC6A4PDPK1 | |
| SCHEMBL12320928 | 0.73 | IDO1 (0.54) | IDO1PIN1FFAR1SLC6A4PDPK1 | |
| SCHEMBL4261413 | 0.71 | CCR2 (0.42) | IDO1PIN1FFAR1 | |
| SCHEMBL1746491 | 0.71 | FFAR1 (0.43) | IDO1PIN1FFAR1 | |
| SCHEMBL4261410 | 0.71 | CCR2 (0.42) | IDO1PIN1FFAR1 | |
| SCHEMBL1745233 | 0.70 | FFAR1 (0.40) | IDO1PIN1FFAR1 | |
| SCHEMBL1745236 | 0.70 | AKR1C3 (0.40) | IDO1PIN1FFAR1 | |
| SCHEMBL12320494 | 0.69 | SLC6A4 (0.51) | IDO1PIN1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368876-A1 | Derivatives of aminoindanes, their preparation and their application in therapeutics | SANOFI (FR) | 2011-09-28 | — | — | EP | disclosed |