Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | GFRA2 | O00451 | 1/20 | 0.35 |
| ▸ | GFRA3 | O60609 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4261410 | 0.82 | CCR2 (0.42) | FFAR1PIN1IDO1 | |
| SCHEMBL4261413 | 0.82 | CCR2 (0.42) | FFAR1PIN1IDO1 | |
| SCHEMBL1745233 | 0.80 | FFAR1 (0.40) | FFAR1PIN1IDO1CHRM4DRD2 | |
| SCHEMBL1745234 | 0.79 | CCR2 (0.42) | FFAR1PIN1IDO1TUBB1GFRA2 | |
| SCHEMBL1745230 | 0.79 | CCR2 (0.42) | FFAR1PIN1IDO1TUBB1GFRA2 | |
| SCHEMBL1746749 | 0.77 | IDO1 (0.49) | FFAR1PIN1IDO1 | |
| SCHEMBL12320178 | 0.76 | IDO1 (0.51) | FFAR1PIN1IDO1 | |
| SCHEMBL1746491 | 0.75 | FFAR1 (0.43) | FFAR1PIN1IDO1 | |
| SCHEMBL1744713 | 0.72 | PIN1 (0.40) | FFAR1PIN1IDO1GFRA2GFRA3 | |
| SCHEMBL2565952 | 0.72 | AKR1C3 (0.53) | AKR1C3APEX1TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385032-A1 | GPR40 Receptor function regulator | Takeda Pharmaceutical Company Limited (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-8008525-B2 | For the 14273 peroxisome proliferator activated receptor; antidiabetic agents, hyperlipidemia, obesity or anorexia; receptor binding assay; drug screening kits | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-08-30 | — | — | US | disclosed |
| US-7960369-B2 | Receptor function regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |