Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.63 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL27979802 | 1.00 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2EPHX1HTR1AHTR2C | |
| Trimethylammonium SCHEMBL5961784 | 0.91 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2EPHX1HTR1AHTR2C | |
| Trimethylammonium SCHEMBL3681199 | 0.91 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2EPHX1HTR1AHTR2C | |
| Trimethylammonium SCHEMBL688148 | 0.87 | ZDHHC20 (0.75) | ZDHHC20ZDHHC2EPHX1TGM2ACHE | |
| SCHEMBL15846309 | 0.85 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2EPHX1HTR1AHTR2C | |
| Sulfuric Acid SCHEMBL2030548 | 0.85 | ZDHHC20 (0.79) | ZDHHC20ZDHHC2EPHX1TGM2ACHE | |
| SCHEMBL127108 | 0.85 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2TGM2MEN1HTT | |
| Trimethylammonium SCHEMBL3679047 | 0.84 | ZDHHC20 (0.43) | ZDHHC20ZDHHC2TGM2ALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL10551560 | 0.84 | ZDHHC20 (0.76) | ZDHHC20ZDHHC2EPHX1TGM2ACHE | |
| Trimethylammonium SCHEMBL27514460 | 0.84 | ZDHHC20 (0.89) | ZDHHC20ZDHHC2EPHX1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071462-A1 | ARTICLES COMPRISING AN OIL CAPTURE POLYMER | THE PROCTER & GAMBLE COMPANY (US) | 2018-04-19 | — | — | WO | claimed |
| US-20180100250-A1 | Articles Comprising an Oil Capture Polymer | THE PROCTER & GAMBLE COMPANY | 2018-04-12 | — | — | US | claimed |
| EP-1558658-B1 | CONTROLLED STRUCTURE COPOLYMER COMPRISING AN AMPHOTERIC OR ZWITTERIONIC PART | RHODIA CHIMIE SA (FR) | 2012-12-19 | — | — | EP | claimed |
| US-8163100-B2 | Synthetic microgel polymer compositions for treating and/or modifying hard surfaces | RHODIA OPERATIONS (FR) | 2012-04-24 | — | — | US | claimed |
| EP-1838762-B1 | COMPOSITION THAT CAN FORM A GEL COMPRISING A COPOLYMER, AND USEFUL COPOLYMERS | RHODIA CHIMIE SA (FR) | 2012-04-18 | — | — | EP | claimed |
| US-7737237-B2 | Controlled structure copolymer comprising an amphoteric or zwitterionic part | PHODIA CHIMIE (FR) | 2010-06-15 | — | — | US | claimed |
| US-20100004152-A1 | Synthetic Microgel Polymer Compositions for Treating and/or Modifying Hard Surfaces | RHODIA OPERATIONS (FR) | 2010-01-07 | — | — | US | claimed |
| US-20060217285-A1 | Controlled structure copolymer comprising an amphoteric or zwitterionic part | RHODIA CHIMIE (FR) | 2006-09-28 | — | — | US | claimed |
| US-8163100-B2 | Synthetic microgel polymer compositions for treating and/or modifying hard surfaces | RHODIA OPERATIONS (FR) | 2012-04-24 | — | — | US | disclosed |
| US-7884056-B2 | star block polymers comprising core and macromolecular branches; for controlling formation of viscoelastic gels | RHODIA CHIMIE (FR) | 2011-02-08 | — | — | US | disclosed |
| US-20100120637-A1 | Composition That Can Form a Gel Comprising a Copolymer, and Useful Copolymers | RHODIA CHIMIE (FR) | 2010-05-13 | — | — | US | disclosed |
| US-20100004152-A1 | Synthetic Microgel Polymer Compositions for Treating and/or Modifying Hard Surfaces | RHODIA OPERATIONS (FR) | 2010-01-07 | — | — | US | disclosed |