Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.53 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 6/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL3681199 | 1.00 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL15846309 | 0.95 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| Methylamine SCHEMBL8020846 | 0.92 | ZDHHC20 (0.54) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| Trimethylammonium SCHEMBL1232298 | 0.91 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| Trimethylammonium SCHEMBL27979802 | 0.91 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| Trimethylammonium SCHEMBL3679047 | 0.87 | ZDHHC20 (0.43) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| Trimethylammonium SCHEMBL21701 | 0.86 | ZDHHC20 (0.62) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| Sulfuric Acid SCHEMBL7864545 | 0.84 | ZDHHC20 (0.66) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| Trimethylammonium SCHEMBL269883 | 0.84 | ZDHHC20 (0.60) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| Trimethylammonium SCHEMBL2124087 | 0.84 | ZDHHC20 (0.60) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984336-B2 | Clothes treatment for dry wrinkle resistance | THE PROCTER & GAMBLE COMPANY (US) | 2006-01-10 | — | — | US | disclosed |
| US-20050015888-A1 | Wrinkle resistant composition | THE PROCTER & GAMBLE COMPANY | 2005-01-27 | — | — | US | disclosed |
| US-20050015887-A1 | Clothes treatment for dry wrinkle resistance | ALTMANN MARKUS WILHELM (BE) | 2005-01-27 | — | — | US | disclosed |
| US-6723253-B2 | TO PRODUCE DRY WRINKLE RESISTANCE IN FABRICS | THE PROCTER & GAMBLE COMPANY | 2004-04-20 | — | — | US | disclosed |
| US-20020130295-A1 | Domestic treatment of fabrics with film-formin materials and blowing agents | THE PROCTER & GAMBLE COMPANY | 2002-09-19 | — | — | US | disclosed |
| US-20020132748-A1 | Clothes treatment for dry wrinkle resistance | PROCTER & GAMBLE COMPANY, THE | 2002-09-19 | — | — | US | disclosed |
| EP-1238137-A2 | WRINKLE RESISTANT COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2002068751-A2 | CLOTHES TREATMENT FOR DRY WRINKLE RESISTANCE | THE PROCTER & GAMBLE COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |
| WO-2002044461-A1 | DOMESTIC TREATMENT OF FABRICS WITH FILM-FORMING MATERIALS AND BLOWING AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 2002-06-06 | — | — | WO | disclosed |
| EP-1201814-A1 | Domestic treatment of fabrics with film-forming materials and blowing agents | THE PROCTER & GAMBLE COMPANY (US) | 2002-05-02 | — | — | EP | disclosed |
| EP-1201816-A1 | Clothes treatment for dry wrinkle resistance | The Procter & Gamble Company (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001031112-A2 | WRINKLE RESISTANT COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2001-05-03 | — | — | WO | disclosed |