Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.31 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.31 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.31 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.31 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.31 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.31 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.31 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.31 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15846955 | 0.95 | ZDHHC20 (0.47) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Trimethylammonium SCHEMBL5961784 | 0.87 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Trimethylammonium SCHEMBL3681199 | 0.87 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Trimethylammonium SCHEMBL156970 | 0.85 | ALDH1A1 (0.54) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Trimethylammonium SCHEMBL1232298 | 0.84 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Trimethylammonium SCHEMBL27979802 | 0.84 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Sulfuric Acid SCHEMBL25209229 | 0.83 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Trimethylammonium SCHEMBL3296333 | 0.83 | ALDH1A1 (0.52) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Trimethylammonium SCHEMBL867400 | 0.83 | ALDH1A1 (0.52) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Trimethylammonium SCHEMBL1232762 | 0.83 | ALDH1A1 (0.52) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582733-B1 | POLYMERS COMPRISING SACCHARIDE SIDE GROUPS AND USE THEREOF | BASF SE (DE) | 2014-06-04 | — | — | EP | disclosed |
| EP-2582733-A1 | POLYMERS COMPRISING SACCHARIDE SIDE GROUPS AND USE THEREOF | BASF SE (DE) | 2013-04-24 | — | — | EP | disclosed |
| WO-2011157777-A1 | POLYMERS COMPRISING SACCHARIDE SIDE GROUPS AND USE THEREOF | BASF SE (DE) | 2011-12-22 | — | — | WO | disclosed |
| US-7662871-B2 | Aqueous polymer dispersions, based on copolymers of vinyl aromatics and butadiene, method for their production and their use as sizing agents for paper | BASF AKTIENGESELLSCHAFT (DE) | 2010-02-16 | — | — | US | disclosed |
| EP-0972110-B2 | METHOD FOR PRODUCING HIGH DRY-STRENGTH PAPER, PULPBOARD AND CARDBOARD | BASF SE (DE) | 2009-03-11 | — | — | EP | disclosed |
| US-7074750-B2 | Treatment method, which promotes the removal of dirt, for the surfaces of textiles and non-textiles | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-11 | — | — | US | disclosed |
| EP-1287104-B1 | USE OF CATIONICALLY MODIFIED, PARTICLE-SHAPED, HYDROPHOBIC POLYMERS AS ADDITION AGENTS IN TEXTILE RINSING OR CARE PRODUCTS AND AS ADDITION AGENTS IN DETERGENTS | BASF AG (DE) | 2006-05-24 | — | — | EP | disclosed |
| EP-1501880-B1 | AQUEOUS POLYMER DISPERSIONS, BASED ON COPOLYMERS OF VINYL AROMATICS AND BUTADIENE, METHOD FOR THEIR PRODUCTION AND THEIR USE AS SIZING AGENTS FOR PAPER | BASF AG (DE) | 2006-02-15 | — | — | EP | disclosed |
| EP-1328573-B1 | HYDROPHILIC, OPEN-CELL, ELASTIC FOAMS WITH A MELAMINE/FORMALDEHYDE RESIN BASE, PRODUCTION THEREOF AND USE THEREOF IN HYGIENE PRODUCTS | BASF AG (DE) | 2005-11-09 | — | — | EP | disclosed |
| US-20050176878-A1 | Aqueous polymer dispersions, based on copolymers of vinyl aromatics and butadiene, method for their production and their use as sizing agents for paper | BASF AKTIENGESELLSCHAFT (DE) | 2005-08-11 | — | — | US | disclosed |
| US-6576086-B1 | Reacting amino- or ammonium-containing polymers with sizing agent; drainage of interfering substances | BASF AKTIENGESELLSCHAFT (DE) | 2003-06-10 | — | — | US | disclosed |
| WO-2002103105-A2 | TREATMENT METHOD, WHICH PROMOTES THE REMOVAL OF DIRT, FOR THE SURFACES OF TEXTILES AND NON-TEXTILES | BASF AKTIENGESELLSCHAFT (DE) | 2002-12-27 | — | — | WO | disclosed |
| EP-0788516-B2 | CATIONIC MODIFICATION PROCESS FOR STARCH AND USE OF CATIONICALLY MODIFIED STARCH | BASF AG (DE) | 2002-10-30 | — | — | EP | disclosed |
| EP-0980450-B1 | METHOD FOR PRODUCING PAPER, PAPERBOARD AND CARDBOARD | BASF AG (DE) | 2002-10-02 | — | — | EP | disclosed |
| EP-1183422-A1 | MODIFYING STARCH WITH CATIONIC POLYMERS AND USE OF THE MODIFIED STARCHES AS DRY-STRENGTH AGENT | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-06 | — | — | EP | disclosed |
| US-6235835-B1 | STARCH IS MODIFIED WITH AT LEAST ONE CATIONIC POLYMER | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |
| US-6160050-A | Polymer-modified starch, method for its production, and its use | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | disclosed |
| WO-2000060167-A1 | MODIFYING STARCH WITH CATIONIC POLYMERS AND USE OF THE MODIFIED STARCHES AS DRY-STRENGTH AGENT | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-12 | — | — | WO | disclosed |
| US-5851300-A | Cationic modification of starch and use of the cationically modified starch | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| EP-0788516-B1 | CATIONIC MODIFICATION PROCESS FOR STARCH AND USE OF CATIONICALLY MODIFIED STARCH | BASF AG (DE) | 1998-07-29 | — | — | EP | disclosed |