Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PON1 | P27169 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12325497 | 0.73 | ALDH1A1 (0.59) | KMT2ACSNK2A2CSNK2BCSNK2A1MAPT | |
| SCHEMBL12325513 | 0.72 | POLB (0.43) | KMT2AKDM4EMEN1CSNK2A2CSNK2B | |
| SCHEMBL13598259 | 0.70 | CSNK2A2 (0.51) | KMT2ARAB9AKDM4EPON1MAPK1 | |
| SCHEMBL12325507 | 0.70 | MAPT (0.54) | RAB9AKDM4EMAPK1CSNK2A2CSNK2B | |
| SCHEMBL12324856 | 0.69 | ABCB1 (0.58) | KMT2ARAB9AKDM4EMEN1MAPT | |
| 4,5,7-Trimethyl-2H-Chromen-2-One SCHEMBL18096558 | 0.69 | KDM4E (0.66) | KMT2ARAB9AKDM4EPON1MAPK1 | |
| SCHEMBL28568538 | 0.68 | CYP3A4 (0.72) | KMT2ARAB9AKDM4EMAPK1MEN1 | |
| SCHEMBL12325496 | 0.68 | ALOX15 (0.43) | KMT2AKDM4EMEN1CSNK2A2CSNK2B | |
| SCHEMBL12325501 | 0.68 | CSNK2A2 (0.44) | KMT2ARAB9AMAPK1MEN1CSNK2A2 | |
| SCHEMBL12325514 | 0.67 | KDM4E (0.49) | KDM4EMAPK1ATMCSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368895-A1 | Ferrocenyl flavonoids | Centre National de la Recherche Scientifique (CNRS) (FR) | 2011-09-28 | — | — | EP | disclosed |