Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 7/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12324852 | 0.73 | HTR2B (0.64) | MAPTALOX15CYP3A4CYP1A2SMN1; SMN2 | |
| SCHEMBL12325485 | 0.72 | TERT (0.54) | KDM4ETP53MAPTLMNAGAA | |
| SCHEMBL19500382 | 0.72 | AR (0.63) | KDM4EMAPTGAACYP1A2POLB | |
| SCHEMBL28903680 | 0.68 | TP53 (0.66) | KDM4ETP53MAPTLMNAGAA | |
| SCHEMBL12325496 | 0.68 | ALOX15 (0.43) | KDM4ETP53MAPTALOX15CYP3A4 | |
| SCHEMBL2426458 | 0.67 | TP53 (0.35) | KDM4ETP53MAPTLMNAGAA | |
| SCHEMBL12325499 | 0.67 | KMT2A (0.50) | KDM4ETP53MAPTPOLBSMN1; SMN2 | |
| SCHEMBL16983575 | 0.66 | HTR2B (0.70) | KDM4EHTR2BHTR2CHTR3A | |
| SCHEMBL5341491 | 0.65 | CYP3A4 (0.50) | KDM4ETP53MAPTLMNAGAA | |
| SCHEMBL12325488 | 0.65 | PTGS1 (0.65) | KDM4ETP53MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368895-A1 | Ferrocenyl flavonoids | Centre National de la Recherche Scientifique (CNRS) (FR) | 2011-09-28 | — | — | EP | disclosed |