Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18854671 | 0.76 | CA1 (0.37) | MEN1KMT2A | |
| SCHEMBL6901506 | 0.72 | MEN1 (0.37) | MEN1KMT2AMAPK1L3MBTL1TP53 | |
| SCHEMBL13295080 | 0.72 | L3MBTL1 (0.48) | MEN1KMT2AMAPK1L3MBTL1TP53 | |
| SCHEMBL24349677 | 0.68 | ALOX15 (0.36) | L3MBTL1ALOX15 | |
| SCHEMBL7327170 | 0.63 | MEN1 (0.48) | MEN1KMT2AMAPK1L3MBTL1TP53 | |
| SCHEMBL6965763 | 0.61 | L3MBTL1 (0.45) | MEN1KMT2AMAPK1L3MBTL1TP53 | |
| SCHEMBL8294084 | 0.61 | CYP2D6 (0.49) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL10787662 | 0.59 | ALOX15 (0.44) | MEN1KMT2AMAPK1L3MBTL1TP53 | |
| SCHEMBL14788303 | 0.59 | MEN1 (0.39) | MEN1KMT2AMAPK1L3MBTL1TP53 | |
| SCHEMBL28924744 | 0.59 | GRIN2D (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011117381-A1 | B-RAF KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-09-29 | — | — | WO | disclosed |