Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965767 | 0.86 | L3MBTL1 (0.46) | L3MBTL1KMT2AMEN1MAPK1TSHR | |
| SCHEMBL6969357 | 0.80 | ALOX5 (0.46) | KMT2AMEN1MAPK1TSHRRAB9A | |
| SCHEMBL13295080 | 0.74 | L3MBTL1 (0.48) | L3MBTL1KMT2AMEN1MAPK1TSHR | |
| SCHEMBL3110283 | 0.72 | L3MBTL1 (0.47) | L3MBTL1KMT2AMEN1MAPK1TSHR | |
| SCHEMBL6957884 | 0.69 | PTGER4 (0.33) | GAASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL24805364 | 0.66 | CYP2C19 (0.43) | L3MBTL1KMT2AMEN1MAPK1TSHR | |
| SCHEMBL6969363 | 0.65 | ALOX5 (0.47) | GAARAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5540699 | 0.65 | L3MBTL1 (0.51) | L3MBTL1KMT2AMEN1MAPK1TSHR | |
| SCHEMBL17788620 | 0.65 | L3MBTL1 (0.40) | L3MBTL1KMT2AMEN1TSHRLMNA | |
| SCHEMBL3113960 | 0.65 | MAPK1 (0.68) | L3MBTL1KMT2AMAPK1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |