Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12330925 | 0.75 | TLR8 (0.47) | TLR8TLR7PDE10A | |
| SCHEMBL12330861 | 0.75 | TLR8 (0.46) | TLR8TLR7PDE10A | |
| SCHEMBL6415271 | 0.75 | TLR8 (0.58) | TLR8TLR7PDE10A | |
| SCHEMBL15764603 | 0.74 | LMNA (0.48) | TLR8TLR7PDE10A | |
| SCHEMBL12330648 | 0.72 | TLR8 (0.44) | TLR8TLR7 | |
| SCHEMBL12331682 | 0.71 | TLR8 (0.36) | TLR8TLR7PDE10A | |
| SCHEMBL27987862 | 0.71 | LMNA (0.43) | — | |
| SCHEMBL12330986 | 0.70 | ACHE (0.47) | TLR8TLR7 | |
| SCHEMBL29698841 | 0.70 | APP (0.62) | — | |
| SCHEMBL12330926 | 0.69 | TLR8 (0.38) | TLR8TLR7PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011115183-A1 | NOVEL MONOCYCLIC PYRIMIDINE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2011-09-22 | — | — | WO | disclosed |