Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12330925 | 0.81 | TLR8 (0.47) | LMNAPDE10ATLR8TLR7KMT2A | |
| SCHEMBL6415271 | 0.80 | TLR8 (0.58) | PDE10ATLR8TLR7KMT2A | |
| SCHEMBL11916234 | 0.78 | TLR8 (0.43) | LMNAPDE10ATLR8TLR7PGK1 | |
| SCHEMBL12330861 | 0.76 | TLR8 (0.46) | LMNAPDE10ATLR8TLR7MAPT | |
| SCHEMBL25166582 | 0.76 | YTHDC1 (0.46) | MAPT | |
| SCHEMBL30329676 | 0.76 | YTHDC1 (0.46) | MAPT | |
| SCHEMBL16094623 | 0.76 | LMNA (0.54) | LMNAPDE10APGK1MAPTKMT2A | |
| SCHEMBL11915815 | 0.76 | PDE10A (0.42) | LMNAPDE10ATLR8TLR7PGK1 | |
| SCHEMBL20614348 | 0.75 | TLR8 (0.68) | PDE10ATLR8TLR7 | |
| SCHEMBL12330866 | 0.74 | TLR8 (0.38) | PDE10ATLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014083327-A1 | ADENINE DERIVATIVES SUITABLE FOR THE TREATMENT OF (INTER ALIA) MUSCULAR DYSTROPHY | MD PHARMA AB (SE) | 2014-06-05 | — | — | WO | disclosed |