Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12233567 | 0.80 | PDK1 (0.51) | MAPTMEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL6868433 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2PDK1 | |
| SCHEMBL14773659 | 0.79 | CHRNB2 (0.42) | SMN1; SMN2PDK1CYP3A4PDE4B | |
| SCHEMBL12331619 | 0.79 | CHRNB2 (0.42) | SMN1; SMN2PDK1CYP3A4PDE4B | |
| SCHEMBL12331071 | 0.79 | CHRNB2 (0.42) | SMN1; SMN2PDK1CYP3A4PDE4B | |
| SCHEMBL12233297 | 0.77 | MAPT (0.46) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL12331002 | 0.76 | PDK1 (0.35) | PDK1 | |
| SCHEMBL12331003 | 0.75 | POLB (0.47) | SMN1; SMN2PDK1PDE4B | |
| SCHEMBL12331039 | 0.74 | HPGD (0.45) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14773445 | 0.73 | PDK1 (0.32) | GAAPDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013036684-A1 | COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS | SATORI PHARMACEUTICALS, INC (US) | 2013-03-14 | — | — | WO | disclosed |
| WO-2011109657-A1 | COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS | SATORI PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |