Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13168166 | 0.85 | TSHR (0.36) | TSHRALDH1A1MAPTNPC1 | |
| SCHEMBL28418177 | 0.83 | ALDH1A1 (0.38) | TSHRALDH1A1MAPTMAPK1 | |
| SCHEMBL2473126 | 0.81 | — | — | |
| SCHEMBL1233099 | 0.81 | — | — | |
| SCHEMBL25414782 | 0.81 | — | — | |
| SCHEMBL22556154 | 0.79 | — | — | |
| SCHEMBL6060785 | 0.78 | MAPT (0.48) | TSHRALDH1A1MAPT | |
| SCHEMBL12181012 | 0.78 | TSHR (0.35) | TSHRMAPT | |
| SCHEMBL12414729 | 0.78 | MAPT (0.48) | TSHRALDH1A1MAPT | |
| SCHEMBL1233344 | 0.77 | NAAA (0.38) | TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2888260-A2 | SUBSTITUTED AZAINDOLE COMPOUNDS, SALTS, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHODS OF USE | Calitor Sciences, LLC (US) | 2015-07-01 | — | — | EP | disclosed |
| WO-2014035846-A2 | SUBSTITUTED AZAINDOLE COMPOUNDS, SALTS, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHODS OF USE | CALITOR SCIENCES, LLC (US) | 2014-03-06 | — | — | WO | disclosed |
| WO-2011017634-A2 | PRODRUGS OF FUSED HETEROCYCLIC INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACORE INC. (US) | 2011-02-10 | — | — | WO | disclosed |
| WO-2004052841-A1 | CARBIDOPA PRODRUGS AND USES THEREOF | XENOPORT, INC. (US) | 2004-06-24 | — | — | WO | disclosed |