Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | WRN | Q14191 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756907 | 0.86 | NAAA (0.43) | NAAAMAPTALDH1A1CYP1A2HPGD | |
| SCHEMBL28810812 | 0.83 | NAAA (0.35) | NAAAMAPTALDH1A1CYP1A2HPGD | |
| SCHEMBL30320231 | 0.82 | MAPT (0.47) | NAAAMAPTALDH1A1CYP1A2HPGD | |
| SCHEMBL2854978 | 0.82 | MAPT (0.47) | NAAAMAPTALDH1A1CYP1A2HPGD | |
| SCHEMBL11004282 | 0.81 | PRKCA (0.41) | ALDH1A1TSHRTDP1L3MBTL1PRKCA | |
| SCHEMBL9756817 | 0.80 | PRKCA (0.39) | NAAAMAPTALDH1A1CYP1A2HPGD | |
| SCHEMBL9756806 | 0.80 | PRKCA (0.39) | NAAAMAPTALDH1A1CYP1A2HPGD | |
| SCHEMBL28418177 | 0.79 | ALDH1A1 (0.38) | MAPTALDH1A1TSHRTDP1LMNA | |
| SCHEMBL27963282 | 0.79 | NAAA (0.35) | NAAAMAPTALDH1A1CYP1A2HPGD | |
| SCHEMBL14410763 | 0.78 | ALDH1A1 (0.42) | NAAAMAPTALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2888260-A2 | SUBSTITUTED AZAINDOLE COMPOUNDS, SALTS, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHODS OF USE | Calitor Sciences, LLC (US) | 2015-07-01 | — | — | EP | disclosed |
| WO-2014035846-A2 | SUBSTITUTED AZAINDOLE COMPOUNDS, SALTS, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHODS OF USE | CALITOR SCIENCES, LLC (US) | 2014-03-06 | — | — | WO | disclosed |
| WO-2011017634-A2 | PRODRUGS OF FUSED HETEROCYCLIC INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACORE INC. (US) | 2011-02-10 | — | — | WO | disclosed |
| EP-0186431-A1 | Anti-hypertensive octahydro-6-azaindole dipeptide derivatives | Pfizer Limited (GB) | 1986-07-02 | — | — | EP | disclosed |