Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 18/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14650336 | 1.00 | CPB2 (0.53) | CPB2CDK5CDK5R1 | |
| SCHEMBL12333989 | 0.84 | CPB2 (0.55) | CPB2CDK5CDK5R1 | |
| SCHEMBL17615544 | 0.83 | CPB2 (0.51) | CPB2CDK5CDK5R1 | |
| SCHEMBL19142387 | 0.82 | CPB2 (0.49) | CPB2 | |
| SCHEMBL14481295 | 0.81 | CPB2 (0.58) | CPB2CDK5CDK5R1 | |
| SCHEMBL14481296 | 0.81 | CPB2 (0.58) | CPB2CDK5CDK5R1 | |
| SCHEMBL26246721 | 0.80 | CPB2 (0.38) | CPB2 | |
| SCHEMBL25626287 | 0.80 | CPB1 (0.41) | CPB2 | |
| SCHEMBL19142536 | 0.79 | CPB2 (0.56) | CPB2 | |
| SCHEMBL19141937 | 0.79 | CPB2 (0.56) | CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2548871-B1 | CYCLOALKYL-SUBSTITUTED IMIDAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2017-07-19 | — | — | EP | disclosed |
| EP-2548871-A1 | CYCLOALKYL-SUBSTITUTED IMIDAZOLE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011115064-A1 | CYCLOALKYL-SUBSTITUTED IMIDAZOLE DERIVATIVE | 第一三共株式会社 (JP) | 2011-09-22 | — | — | WO | disclosed |