SCHEMBL17615544

SCHEMBL17615544

OCc1cn(C2CCCCC2)cn1

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 15/20 0.51
CDK5 Q00535 3/20 0.40
CDK5R1 Q15078 3/20 0.40
CPB1 P15086 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12333367 0.83 CPB2 (0.53) CPB2CDK5CDK5R1
SCHEMBL14650336 0.83 CPB2 (0.53) CPB2CDK5CDK5R1
SCHEMBL25626287 0.83 CPB1 (0.41) CPB2CPB1
SCHEMBL26246721 0.83 CPB2 (0.38) CPB2
SCHEMBL22920150 0.82 CPB2 (0.54) CPB2CDK5CDK5R1CPB1
SCHEMBL26246698 0.82 CPB2 (0.48) CPB2CDK5CDK5R1CPB1
SCHEMBL12333989 0.80 CPB2 (0.55) CPB2CDK5CDK5R1
SCHEMBL5470662 0.78 CPB2 (0.54) CPB2CDK5CDK5R1CPB1
SCHEMBL19141762 0.78 CPB2 (0.54) CPB2CDK5CDK5R1CPB1
SCHEMBL20080534 0.78 CPB2 (0.54) CPB2CDK5CDK5R1CPB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230286973-A1 PROTEIN SECRETION INHIBITORS ENODIA THERAPEUTICS SAS (FR) 2023-09-14 US disclosed
US-20230286973-A1 PROTEIN SECRETION INHIBITORS ENODIA THERAPEUTICS SAS (FR) 2023-09-14 US disclosed
EP-3470399-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2020-11-04 EP disclosed
US-10633346-B2 Methods for producing optically active valeric acid derivatives DAIICHI SANKYO COMPANY, LIMITED (JP) 2020-04-28 US disclosed
EP-3196192-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2019-07-03 EP disclosed
US-20190055201-A1 METHODS FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVES DAIICHI SANKYO COMPANY, LIMITED (JP) 2019-02-21 US disclosed
US-9938242-B2 Methods for producing optically active valeric acid derivatives DAIICHI SANKYO COMPANY, LIMITED (JP) 2018-04-10 US disclosed
US-20180029993-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2018-02-01 US disclosed
US-20170291878-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2017-10-12 US disclosed
EP-3196193-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2017-07-26 EP disclosed
EP-3196192-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2017-07-26 EP disclosed
WO-2016043253-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVE 第一三共株式会社 2016-03-24 WO disclosed
WO-2016043254-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVE 第一三共株式会社 2016-03-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190055201-A1 METHODS FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVES ALAD, GRHPR, ME1 CPB2 1489/4885CDK5 2516/4885CDK5R1 3363/4885
US-20180029993-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVE ALAD, GRHPR, ME1 CPB2 1887/4885CDK5 2527/4885CDK5R1 3315/4885
US-20230286973-A1 PROTEIN SECRETION INHIBITORS SEC61B, SEC61A1, SEC61G CPB2 764/4885CDK5 3190/4885CDK5R1 2751/4885
US-20170291878-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE VALERIC ACID DERIVATIVE ALAD, GRHPR, ME1 CPB2 1945/4885CDK5 2614/4885CDK5R1 3369/4885
US-10633346-B2 Methods for producing optically active valeric acid derivatives ALAD, GRHPR, ME1 CPB2 1489/4885CDK5 2516/4885CDK5R1 3363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.