Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | IL18 | Q14116 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11300462 | 0.80 | CA1 (0.50) | SAE1UBA2MAPTLMNATSHR | |
| SCHEMBL29072381 | 0.76 | SAE1 (0.47) | SAE1UBA2MAPTLMNATSHR | |
| SCHEMBL16367907 | 0.76 | CA1 (0.41) | SAE1UBA2MAPTLMNATSHR | |
| SCHEMBL29072383 | 0.76 | SAE1 (0.47) | SAE1UBA2MAPTLMNATSHR | |
| SCHEMBL183353 | 0.74 | ALDH1A1 (0.52) | SAE1UBA2MAPTLMNATSHR | |
| SCHEMBL18677358 | 0.73 | MMP2 (0.40) | SAE1UBA2MAPTLMNATSHR | |
| SCHEMBL5516545 | 0.72 | ALDH1A1 (0.44) | SAE1UBA2MAPTCA1CA2 | |
| SCHEMBL7415060 | 0.72 | CYP1A1 (0.47) | MAPTTSHRCA1CA2CA12 | |
| SCHEMBL7746721 | 0.72 | MAPT (0.56) | MAPTLMNAHTTCA1CA2 | |
| SCHEMBL3524179 | 0.72 | CA12 (0.33) | CA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834224-B1 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND SALTS THEREOF | MSN LAB LTD (IN) | 2018-06-06 | — | — | EP | disclosed |
| US-20110224441-A1 | METHOD FOR THE PREPARATION OF DABIGATRAN AND ITS INTERMEDIATES | ZENTIVA K.S. (CZ) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224441-A1 | METHOD FOR THE PREPARATION OF DABIGATRAN AND ITS INTERMEDIATES | VKORC1L1, VKORC1, CYP2C9 | SAE1 3470/4885UBA2 2745/4885MAPT 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.