SCHEMBL5516545

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6418566	0.98	PRSS1 (0.46)	ALDH1A1MAPTPRSS1CA1CA2
	SCHEMBL5712390	0.98	PRSS1 (0.46)	ALDH1A1MAPTPRSS1CA1CA2
	SCHEMBL5712397	0.98	PRSS1 (0.46)	ALDH1A1MAPTPRSS1CA1CA2
	SCHEMBL31475206	0.90	ALDH1A1 (0.50)	ALDH1A1PRSS1CA2SAE1UBA2
	SCHEMBL11500089	0.90	MGLL (0.50)	LOXL2GAAABCG2CYP2A6
	SCHEMBL23961158	0.89	ALDH1A1 (0.49)	ALDH1A1PRSS1SAE1UBA2F2
	SCHEMBL11475163	0.89	MGLL (0.52)	LOXL2GAAABCG2CYP2A6
	SCHEMBL11465958	0.89	MGLL (0.52)	LOXL2GAAABCG2CYP2A6
	SCHEMBL5283982	0.89	MGLL (0.52)	LOXL2GAAABCG2CYP2A6
	SCHEMBL11177848	0.89	ALDH1A1 (0.49)	ALDH1A1PRSS1SAE1UBA2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.