Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12306526 | 0.93 | KDM4E (0.46) | PDK2KDM4EL3MBTL1ATMHDAC4 | |
| SCHEMBL12306587 | 0.91 | L3MBTL1 (0.47) | PDK2KDM4EL3MBTL1ATMHDAC4 | |
| SCHEMBL12414494 | 0.91 | KDM4E (0.43) | PDK2KDM4EL3MBTL1ATMHDAC4 | |
| SCHEMBL12306583 | 0.89 | KDM4E (0.42) | PDK2KDM4EL3MBTL1ATMHDAC4 | |
| SCHEMBL13382211 | 0.89 | KDM4E (0.42) | PDK2KDM4EL3MBTL1ATMHDAC4 | |
| SCHEMBL22237673 | 0.88 | PDK2 (0.34) | PDK2KDM4EL3MBTL1ATMHDAC4 | |
| SCHEMBL20232324 | 0.88 | KDM4E (0.41) | PDK2KDM4EL3MBTL1ATMHDAC4 | |
| SCHEMBL18777955 | 0.88 | KDM4E (0.41) | PDK2KDM4EL3MBTL1ATMHDAC4 | |
| SCHEMBL24729769 | 0.88 | KDM4E (0.43) | PDK2KDM4EL3MBTL1ATMHDAC4 | |
| SCHEMBL29850305 | 0.88 | KDM4E (0.43) | PDK2KDM4EL3MBTL1ATMHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013160-B2 | Fluorene-based derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20100277063-A1 | FLUORENE-BASED DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100277063-A1 | FLUORENE-BASED DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | LEF1, FLNA, AFF2 | PDK2 1028/4885KDM4E 1471/4885L3MBTL1 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.