Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 16/20 | 0.74 |
| ▸ | FKBP4 | Q02790 | 2/20 | 0.49 |
| ▸ | FKBP5 | Q13451 | 2/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1233420 | 1.00 | FKBP1A (0.74) | FKBP1AFKBP4FKBP5ABCC1MMP2 | |
| SCHEMBL5966161 | 0.96 | FKBP1A (0.80) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL7155851 | 0.96 | FKBP1A (0.80) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL7245239 | 0.92 | FKBP1A (0.66) | FKBP1AFKBP4FKBP5ABCC1MMP2 | |
| SCHEMBL11998537 | 0.87 | FKBP1A (0.56) | FKBP1AMMP2ANPEP | |
| SCHEMBL1233000 | 0.84 | FKBP1A (0.73) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL5966113 | 0.84 | FKBP1A (0.63) | FKBP1AFKBP5MMP2ANPEP | |
| SCHEMBL14407836 | 0.84 | FKBP1A (0.63) | FKBP1AFKBP4FKBP5ABCC1MMP2 | |
| SCHEMBL11161406 | 0.81 | ACE (0.50) | FKBP1AMMP2ANPEP | |
| SCHEMBL14407784 | 0.79 | ITGB3 (0.53) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110151006-A1 | STIMULI-RESPONSIVE HYDROGEL | ETH ZURICH (CH) | 2011-06-23 | — | — | US | disclosed |
| EP-2285418-A1 | STIMULI-RESPONSIVE HYDROGEL | ETH Zurich (CH) | 2011-02-23 | — | — | EP | disclosed |
| WO-2009146929-A1 | STIMULI-RESPONSIVE HYDROGEL | ETH Zürich (CH) | 2009-12-10 | — | — | WO | disclosed |