Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PYGL | P06737 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.48 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334655 | 0.88 | RORC (0.71) | RORCMAPK1MEN1LMNAPOLB | |
| SCHEMBL12334579 | 0.86 | SNCA (0.59) | RORCMAPK1LMNAMAPTKMT2A | |
| SCHEMBL12334377 | 0.84 | RORC (0.58) | RORCMAPK1MEN1LMNAPOLB | |
| SCHEMBL31078114 | 0.82 | RORC (1.00) | RORCMAPK1MEN1LMNAPOLB | |
| SCHEMBL12334368 | 0.82 | RORC (1.00) | RORCMAPK1MEN1LMNAPOLB | |
| SCHEMBL14228287 | 0.80 | PYGL (0.59) | MAPK1MEN1KMT2APYGLGRM4 | |
| SCHEMBL94746 | 0.79 | PYGL (0.54) | MAPK1MEN1LMNAMAPTKMT2A | |
| SCHEMBL17142908 | 0.79 | JAK2 (0.61) | MAPK1MEN1LMNAPOLBKMT2A | |
| SCHEMBL17143174 | 0.79 | PYGL (0.54) | MAPK1MEN1MAPTKMT2APYGL | |
| SCHEMBL5314331 | 0.79 | RORC (0.79) | RORCMAPK1MEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011115892-A1 | MODULATORS OF THE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTORS | GRIFFIN PATRICK R (US) | 2011-09-22 | — | — | WO | disclosed |