Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | TAS2R38 | P59533 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14016448 | 0.77 | TGM2 (0.45) | TGM2GAATAS2R38HSD17B10KMT2A | |
| SCHEMBL21414659 | 0.76 | TGM2 (0.48) | TGM2GAATAS2R38HSD17B10KMT2A | |
| SCHEMBL799413 | 0.75 | ALDH1A1 (0.44) | TGM2GAATAS2R38HSD17B10KMT2A | |
| SCHEMBL20869312 | 0.74 | KMT2A (0.39) | TGM2GAATAS2R38HSD17B10KMT2A | |
| SCHEMBL21944495 | 0.73 | MAOB (0.42) | TGM2GAATAS2R38HSD17B10KMT2A | |
| SCHEMBL24318333 | 0.71 | MAPT (0.52) | GAAHSD17B10KMT2ARAB9AMEN1 | |
| SCHEMBL19450424 | 0.71 | TGM2 (0.42) | TGM2GAATAS2R38HSD17B10KMT2A | |
| SCHEMBL22700707 | 0.69 | TGM2 (0.46) | TGM2GAATAS2R38HSD17B10KMT2A | |
| SCHEMBL12862829 | 0.68 | TGM2 (0.48) | TGM2GAATAS2R38HSD17B10KMT2A | |
| SCHEMBL27657876 | 0.68 | MMP1 (0.63) | CYP1A2SMN1; SMN2LMNAALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368558-A1 | Azo compounds reducing formation and toxicity of amyloid beta aggregation intermediates | Mdc Max-Delbrück-Centrum Für Molekulare Medizin Berlin - Buch (DE) | 2011-09-28 | — | — | EP | disclosed |