SCHEMBL12342186

SCHEMBL12342186

CCN(CCOC)c1ccc(C(c2ccccc2)c2ccc(N(CC)CCOC)cc2C)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.43
HTT P42858 3/20 0.43
GAA P10253 1/20 0.43
PKM P14618 1/20 0.43
MCL1 Q07820 1/20 0.43
CRHR1 P34998 4/20 0.38
S100B P04271 1/20 0.37
NR1H2 P55055 2/20 0.36
NR1H3 Q13133 2/20 0.36
ALDH1A1 P00352 4/20 0.36
MAPK1 P28482 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
GFER P55789 1/20 0.36
LMNA P02545 4/20 0.35
HSD17B10 Q99714 4/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35
ALOX15 P16050 1/20 0.35
RAB9A P51151 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12342185 0.91 S100B (0.41) MAPTHTTGAAPKMMCL1
SCHEMBL7952524 0.86 S100B (0.49) MAPTHTTGAAPKMMCL1
SCHEMBL133593 0.86 S100B (0.49) MAPTHTTGAAPKMMCL1
SCHEMBL7650155 0.84 MAPT (0.61) MAPTHTTGAAPKMMCL1
SCHEMBL12342188 0.82 MAPT (0.44) MAPTHTTGAAPKMMCL1
SCHEMBL12342183 0.81 MAPT (0.44) MAPTHTTGAAPKMMCL1
SCHEMBL19886263 0.81 MAPT (0.44) MAPTHTTGAAPKMMCL1
SCHEMBL10514637 0.81 HTT (0.52) MAPTHTTGAAPKMMCL1
SCHEMBL6252652 0.80 TSHR (0.53) MAPTHTTGAAPKMMCL1
SCHEMBL13649925 0.80 S100B (0.45) MAPTHTTGAAPKMMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8268521-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-09-18 US disclosed
US-8268521-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-09-18 US disclosed
US-20100151366-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2010-06-17 US disclosed
US-20100151366-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2010-06-17 US disclosed