SCHEMBL12342189

SCHEMBL12342189

CCN(CCO)c1ccc(C(c2ccc(OC)cc2)c2ccc(N(CC)CCO)cc2C)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.50
HTT P42858 3/20 0.50
GAA P10253 2/20 0.50
PKM P14618 1/20 0.50
MCL1 Q07820 1/20 0.50
LMNA P02545 6/20 0.47
KMT2A Q03164 4/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
TP53 P04637 2/20 0.47
NPSR1 Q6W5P4 2/20 0.47
ATM Q13315 1/20 0.47
SLC2A1 P11166 1/20 0.41
HSD17B10 Q99714 2/20 0.38
MEN1 O00255 2/20 0.37
S100B P04271 1/20 0.35
HPGD P15428 1/20 0.35
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
PSMD14 O00487 1/20 0.35
MITF O75030 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3190991 0.90 SLC2A1 (0.47) MAPTHTTGAAPKMMCL1
SCHEMBL12342190 0.89 MAPT (0.55) MAPTHTTGAAPKMMCL1
SCHEMBL7650155 0.85 MAPT (0.61) MAPTHTTGAAPKMMCL1
SCHEMBL5009578 0.83 MAPT (0.59) MAPTHTTGAAPKMMCL1
SCHEMBL5010104 0.81 CNR2 (0.46) MAPTHTTGAAPKMMCL1
SCHEMBL12342188 0.80 MAPT (0.44) MAPTHTTGAAPKMMCL1
SCHEMBL10952039 0.80 S100B (0.53) MAPTHTTGAAPKMMCL1
SCHEMBL5665650 0.79 SLC2A1 (0.47) MAPTHTTGAAPKMLMNA
SCHEMBL12371968 0.79 MAPT (0.49) MAPTHTTGAAPKMMCL1
SCHEMBL12342185 0.79 S100B (0.41) MAPTHTTGAAPKMMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8268521-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-09-18 US disclosed
US-8268521-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-09-18 US disclosed
US-20100151366-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2010-06-17 US disclosed
US-20100151366-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2010-06-17 US disclosed