SCHEMBL123427

SCHEMBL123427

Cc1cc(=O)c2ccccc2o1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 7/20 0.59
PARP1 P09874 4/20 0.59
TNKS2 Q9H2K2 4/20 0.59
MAOB P27338 2/20 0.59
PARP2 Q9UGN5 2/20 0.59
ACHE P22303 1/20 0.58
HPGD P15428 5/20 0.56
SMN1; SMN2 Q16637 5/20 0.56
NPC1 O15118 4/20 0.56
RAB9A P51151 4/20 0.56
CYP3A4 P08684 3/20 0.56
CYP1B1 Q16678 2/20 0.56
GABRP O00591 2/20 0.56
GABRD O14764 2/20 0.56
TP53 P04637 2/20 0.56
GABRA1 P14867 2/20 0.56
GABRB1 P18505 2/20 0.56
GABRG2 P18507 2/20 0.56
GABRB3 P28472 2/20 0.56
GABRA5 P31644 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29380373 1.00 TNKS (0.59) TNKSPARP1TNKS2MAOBPARP2
SCHEMBL30876961 0.85 ACHE (0.49) TNKSPARP1TNKS2MAOBPARP2
Ethyl Acetate SCHEMBL11110265 0.83 KDM4E (0.60) TNKSMAOBACHEHPGDSMN1; SMN2
SCHEMBL31217562 0.79 ACHE (0.58) TNKSACHEHPGDSMN1; SMN2CYP3A4
2,7-Dimethylchromone SCHEMBL7600130 0.78 ALDH1A1 (0.64) TNKSPARP1TNKS2MAOBPARP2
SCHEMBL266614 0.78 MAPT (0.63) ACHEHPGDSMN1; SMN2NPC1RAB9A
Flavone SCHEMBL27560931 0.77 TNKS (0.85) TNKSPARP1TNKS2MAOBPARP2
SCHEMBL4373327 0.76 HPGD (0.45) TNKSMAOBACHEHPGDSMN1; SMN2
SCHEMBL5340573 0.76 TNKS (0.59) TNKSPARP1TNKS2MAOBPARP2
SCHEMBL10654593 0.76 CYP3A4 (0.78) TNKSPARP1TNKS2MAOBPARP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119019483-A Methyl chromone compound and preparation method and application thereof 石家庄以岭药业股份有限公司 2024-11-26 CN claimed
CN-117567419-A Synthesis method of 3-amine methyl primary ketone derivative 深圳职业技术大学 2024-02-20 CN claimed
CN-113527244-B 5-methyl chromone derivative and synthetic method and application thereof 海南医学院 2023-02-03 CN claimed
CN-108558859-B Preparation and application of visible long-wave Hg2+ fluorescent probe based on benzopyran 湖北大学 2021-08-24 CN claimed
CN-106478576-B A kind of fluorescence probe and the preparation method and application thereof for detecting carboxy-lesterase 华南理工大学 2019-01-18 CN claimed
CN-106478576-A A kind of for detecting fluorescence probe of carboxy-lesterase and preparation method and application 华南理工大学 2017-03-08 CN claimed
CN-106107406-A Improve the method for the stability of sweetness enhancers and comprise the compositions of stable sweetness enhancers 赛诺米克斯公司 2016-11-16 CN claimed
CN-105327336-A Chinese herbal medicine containing herba catharanthi rosei, aloes, radix zanthoxyli and mint, skin absorbable lotion and diet therapy XIE YOUZHU 2016-02-17 CN claimed
CN-103153096-A Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers SENOMYX INC 2013-06-12 CN claimed
US-4513145-A BACTERICIDES, URINARY TRACT DISORDERS; CEPH M INTERMEDIATES EISAI CO., LTD. (JP) 1985-04-23 US claimed
EP-0114899-A1 2-Methylchromone derivatives and their preparation process Eisai Co., Ltd. (JP) 1984-08-08 EP claimed
JP-63030483-A None JP disclosed
WO-2025129358-A1 STABLE FILM FORMULATIONS FOR HIGH LOADING OF LOW MELTING POINT ACTIVES INTELGENX CORP. (CA) 2025-06-26 WO disclosed
US-12162863-B2 Modulators of stimulator of interferon genes (STING) Ryvu Therapeutics S.A. (PL) 2024-12-10 US disclosed
CN-119019483-A Methyl chromone compound and preparation method and application thereof 石家庄以岭药业股份有限公司 2024-11-26 CN disclosed
EP-0114899-A1 2-Methylchromone derivatives and their preparation process Eisai Co., Ltd. (JP) 1984-08-08 EP disclosed
EP-0114899-A1 2-Methylchromone derivatives and their preparation process Eisai Co., Ltd. (JP) 1984-08-08 EP disclosed
EP-0114899-A1 2-Methylchromone derivatives and their preparation process Eisai Co., Ltd. (JP) 1984-08-08 EP disclosed
US-4428955-A ALLERGIC DISEASES BOEHRINGER MANNHEIM GMBH (DE) 1984-01-31 US disclosed
JP-S06330483-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12162863-B2 Modulators of stimulator of interferon genes (STING) STING1, IRF3, CGAS TNKS 342/4885PARP1 2212/4885TNKS2 391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.