Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | F13A1 | P00488 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | TGM1 | P22735 | 1/20 | 0.32 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12345111 | 0.88 | RAB9A (0.33) | STAT3NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL12345119 | 0.87 | RAB9A (0.33) | STAT3NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL12345114 | 0.86 | STAT3 (0.32) | STAT3NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL13108647 | 0.85 | AR (0.36) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL12345126 | 0.85 | RAB9A (0.34) | STAT3NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL14302918 | 0.83 | ATM (0.48) | NPSR1KDM4EGAAMAPTRAB9A | |
| SCHEMBL12345046 | 0.83 | RAB9A (0.36) | STAT3NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL12345092 | 0.83 | RAB9A (0.36) | STAT3NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL12345095 | 0.82 | CTSK (0.35) | STAT3NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL13123351 | 0.76 | RAB9A (0.47) | NPSR1KDM4EGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049104-B1 | PYRROLIDINONE ANILINES AS PROGESTERONE RECEPTOR MODULATORS | GLAXOSMITHKLINE LLC (US) | 2012-09-19 | — | — | EP | disclosed |
| WO-2008021796-A2 | PYRROLIDINONE ANILINES AS PROGESTERONE RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |