Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12345114 | 0.92 | STAT3 (0.32) | RAB9ANPC1STAT3GAAMAPT | |
| SCHEMBL12345119 | 0.90 | RAB9A (0.33) | RAB9ANPC1STAT3GAAMAPT | |
| SCHEMBL12345126 | 0.89 | RAB9A (0.34) | RAB9ANPC1STAT3GAAMAPT | |
| SCHEMBL12345095 | 0.88 | CTSK (0.35) | RAB9ANPC1STAT3GAAMAPT | |
| SCHEMBL12345089 | 0.88 | STAT3 (0.33) | RAB9ANPC1STAT3GAAMAPT | |
| SCHEMBL14302918 | 0.87 | ATM (0.48) | RAB9AGAAMAPTNPSR1KDM4E | |
| SCHEMBL12345046 | 0.86 | RAB9A (0.36) | RAB9ANPC1STAT3GAAMAPT | |
| SCHEMBL12345092 | 0.86 | RAB9A (0.36) | RAB9ANPC1STAT3GAAMAPT | |
| SCHEMBL27777714 | 0.84 | RORC (0.40) | GAAALDH1A1LMNA | |
| SCHEMBL13108632 | 0.84 | RORC (0.40) | GAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049104-B1 | PYRROLIDINONE ANILINES AS PROGESTERONE RECEPTOR MODULATORS | GLAXOSMITHKLINE LLC (US) | 2012-09-19 | — | — | EP | disclosed |
| WO-2008021796-A2 | PYRROLIDINONE ANILINES AS PROGESTERONE RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |