Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12903455 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA1CA2TAAR1 | |
| SCHEMBL17438169 | 0.83 | TSHR (0.48) | TSHRCYP3A4TAAR1HIF1ANFKB1 | |
| SCHEMBL8746277 | 0.81 | TSHR (0.42) | TSHRCYP3A4CA1CA2TAAR1 | |
| SCHEMBL5988792 | 0.80 | LMNA (0.56) | TSHRCYP3A4CA1CA2TAAR1 | |
| SCHEMBL7146297 | 0.80 | TAAR1 (0.59) | TSHRCYP3A4CA1CA2TAAR1 | |
| SCHEMBL5267546 | 0.78 | CA1 (0.43) | TSHRCA1CA2TAAR1HIF1A | |
| SCHEMBL15865826 | 0.77 | TSHR (0.48) | TSHRCYP3A4TAAR1TDP1PLAU | |
| SCHEMBL27577466 | 0.77 | ABAT (0.46) | TSHRCYP3A4TAAR1HIF1ANFKB1 | |
| SCHEMBL14544262 | 0.77 | TSHR (0.48) | TSHRCYP3A4TAAR1TDP1PLAU | |
| SCHEMBL19417918 | 0.76 | CA1 (0.41) | TSHRCA1CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115153-B2 | Aza metal complexes | CANON KABUSHIKI KAISHA (JP) | 2015-08-25 | — | — | US | disclosed |
| US-9115153-B2 | Aza metal complexes | CANON KABUSHIKI KAISHA (JP) | 2015-08-25 | — | — | US | disclosed |
| US-9115153-B2 | Aza metal complexes | CANON KABUSHIKI KAISHA (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140275521-A1 | Aza metal complexes | CANON KABUSHIKI KAISHA (JP) | 2014-09-18 | — | — | US | disclosed |
| US-20140275521-A1 | Aza metal complexes | CANON KABUSHIKI KAISHA (JP) | 2014-09-18 | — | — | US | disclosed |
| US-20140275521-A1 | Aza metal complexes | CANON KABUSHIKI KAISHA (JP) | 2014-09-18 | — | — | US | disclosed |
| US-8772475-B2 | AZA compounds and production method thereof, and metal complexes as MRI contrast agents | CANON KABUSHIKI KAISHA (JP) | 2014-07-08 | — | — | US | disclosed |
| US-8772475-B2 | AZA compounds and production method thereof, and metal complexes as MRI contrast agents | CANON KABUSHIKI KAISHA (JP) | 2014-07-08 | — | — | US | disclosed |
| US-8772475-B2 | AZA compounds and production method thereof, and metal complexes as MRI contrast agents | CANON KABUSHIKI KAISHA (JP) | 2014-07-08 | — | — | US | disclosed |
| US-20110028713-A1 | AZA COMPOUNDS AND PRODUCTION METHOD THEREOF, AND METAL COMPLEXES AS MRI CONTRAST AGENTS | KYOTO UNIVERSITY (JP) | 2011-02-03 | — | — | US | disclosed |
| US-20110028713-A1 | AZA COMPOUNDS AND PRODUCTION METHOD THEREOF, AND METAL COMPLEXES AS MRI CONTRAST AGENTS | KYOTO UNIVERSITY (JP) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275521-A1 | Aza metal complexes | DNMT1, HDAC10, AZI2 | TSHR 1884/4885CYP3A4 2018/4885CA1 480/4885 |
| US-20110028713-A1 | AZA COMPOUNDS AND PRODUCTION METHOD THEREOF, AND METAL COMPLEXES AS MRI CONTRAST AGENTS | DNMT1, AZI2, HDAC10 | TSHR 1688/4885CYP3A4 1608/4885CA1 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.