Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | PGK1 | P00558 | 2/20 | 0.34 |
| ▸ | PGK2 | P07205 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19417918 | 0.82 | CA1 (0.41) | CA1CA2PGK1PGK2FAAH | |
| SCHEMBL5988152 | 0.80 | NOS3 (0.41) | CA1CA2FAAHTSHRMAPK1 | |
| SCHEMBL1234653 | 0.78 | TSHR (0.39) | CA1CA2TSHRTDP1TAAR1 | |
| SCHEMBL12903455 | 0.78 | TSHR (0.39) | CA1CA2TSHRTDP1TAAR1 | |
| SCHEMBL11511609 | 0.78 | ESR1 (0.48) | CA1CA2PGK1PGK2TSHR | |
| SCHEMBL9798184 | 0.78 | CA1 (0.41) | CA1CA2PGK1PGK2FAAH | |
| SCHEMBL5988792 | 0.77 | LMNA (0.56) | CA1CA2FAAHTSHRMAPK1 | |
| SCHEMBL7146297 | 0.77 | TAAR1 (0.59) | CA1CA2TSHRMAPK1TDP1 | |
| SCHEMBL2376299 | 0.76 | ESR1 (0.35) | PGK1PGK2TSHRMAPK1TDP1 | |
| SCHEMBL97582 | 0.76 | CA1 (0.52) | CA1CA2FAAHTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812388-A1 | SULFONAMIDE PERT-SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE | Decode Genetics (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006044000-A1 | SULFONAMIDE PERT-SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE | DECODE GENETICS (US) | 2006-04-27 | — | — | WO | disclosed |
| EP-1257558-A1 | METHODS FOR SYNTHESIS OF ALPHA-D-GAL (1- 3) GAL-CONTAINING OLIGOSACCHARIDES | Alchemia Pty Ltd (AU) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001051499-A1 | METHODS FOR SYNTHESIS OF α-D-GAL (1→3) GAL-CONTAINING OLIGOSACCHARIDES | ALCHEMIA PTY LTD (AU) | 2001-07-19 | — | — | WO | disclosed |