Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | VHL | P40337 | 1/20 | 0.37 |
| ▸ | ELOC | Q15369 | 1/20 | 0.37 |
| ▸ | ELOB | Q15370 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17438169 | 0.87 | TSHR (0.48) | TSHRCYP3A4TAAR1HIF1AHTR3A | |
| SCHEMBL1234653 | 0.81 | TSHR (0.39) | TSHRCYP3A4TAAR1HIF1AHTR3A | |
| SCHEMBL12903455 | 0.81 | TSHR (0.39) | TSHRCYP3A4TAAR1HIF1AHTR3A | |
| SCHEMBL27577466 | 0.81 | ABAT (0.46) | TSHRCYP3A4TAAR1HIF1AHTR3A | |
| SCHEMBL14544262 | 0.81 | TSHR (0.48) | TSHRCYP3A4TAAR1TDP1ADRB2 | |
| SCHEMBL15865826 | 0.81 | TSHR (0.48) | TSHRCYP3A4TAAR1TDP1ADRB2 | |
| SCHEMBL7455698 | 0.81 | LMNA (0.58) | TSHRCYP3A4TAAR1HIF1AHTR3A | |
| SCHEMBL1338106 | 0.79 | TSHR (0.44) | TSHRCYP3A4TAAR1HIF1AHTR3A | |
| SCHEMBL14533503 | 0.79 | TSHR (0.46) | TSHRCYP3A4PRSS1PRSS2PRSS3 | |
| SCHEMBL3236662 | 0.79 | TSHR (0.46) | TSHRPRSS1PRSS2PRSS3VHL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369379-B1 | Image forming method | KONISHIROKU PHOTO IND (JP) | 1997-02-12 | — | — | EP | disclosed |
| US-4985337-A | ACID GENERATING AGENT AND COMPOUND DECOMPOSABLE WITH ACID | KONICA CORPORATION (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0369379-A2 | Image forming method | KONICA CORPORATION (JP) | 1990-05-23 | — | — | EP | disclosed |
| EP-0022571-B1 | PHOTOSENSITIVE MIXTURE AND METHOD OF PRODUCTION OF RELIEF IMAGES | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-12-22 | — | — | EP | disclosed |
| US-4311782-A | POLYETHER OF ORTHOCARBOXYLIC ESTER | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-19 | — | — | US | disclosed |
| EP-0022571-A1 | Photosensitive mixture and method of production of relief images | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-21 | — | — | EP | disclosed |
| US-4186185-A | Compositions comprising arylene substituted poly(orthoesters) containing useful agents | ALZA CORPORATION (US) | 1980-01-29 | — | — | US | disclosed |
| US-4155740-A | SUSTAINED RELEASE | ALZA CORPORATION (US) | 1979-05-22 | — | — | US | disclosed |
| US-4136252-A | POLYETHERS, SUSTAINED RELEASE COATINGS | ALZA CORPORATION (US) | 1979-01-23 | — | — | US | disclosed |
| US-4119579-A | Polymeric orthoesters | ALZA CORPORATION (US) | 1978-10-10 | — | — | US | disclosed |
| US-4066747-A | Polymeric orthoesters housing beneficial drug for controlled release therefrom | ALZA CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |