Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.53 |
| ▸ | CNR2 | P34972 | 8/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1234583 | 0.75 | ALDH1A1 (0.46) | CNR1CNR2GPR55ALDH1A1TP53 | |
| SCHEMBL1236073 | 0.74 | CNR2 (0.54) | CNR1CNR2GPR55ALDH1A1TP53 | |
| SCHEMBL2271081 | 0.74 | CNR1 (0.59) | CNR1CNR2GPR55ALDH1A1TP53 | |
| SCHEMBL1236052 | 0.72 | PTGS2 (0.50) | CNR1CNR2GPR55ALDH1A1TP53 | |
| SCHEMBL1236537 | 0.68 | CNR1 (0.51) | CNR1CNR2GPR55ALDH1A1TP53 | |
| SCHEMBL18876269 | 0.68 | KDM4E (0.58) | ALDH1A1TP53GAATSHRHTT | |
| SCHEMBL18876426 | 0.67 | KDM4E (0.57) | ALDH1A1TP53GAATSHRSMN1; SMN2 | |
| SCHEMBL2162023 | 0.67 | ALDH1A1 (0.56) | CNR1CNR2GPR55ALDH1A1TP53 | |
| SCHEMBL18044490 | 0.66 | KDM4E (0.39) | ALDH1A1TP53GAANPC1LMNA | |
| SCHEMBL27911329 | 0.66 | KDM4E (0.39) | ALDH1A1TP53GAANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476309-B2 | Benzofuran cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | claimed |
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | claimed |
| WO-2011022679-A2 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2011-02-24 | — | — | WO | claimed |
| US-8476309-B2 | Benzofuran cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476309-B2 | Benzofuran cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476309-B2 | Benzofuran cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| WO-2011022679-A2 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2011-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | CNR1, CNR2, GPR18 | CNR1 1/4885CNR2 2/4885GPR55 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.