Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | GLA | P06280 | 2/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13533840 | 0.94 | NPC1 (0.71) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL34879 | 0.88 | RAB9A (0.74) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13533794 | 0.87 | NPC1 (0.60) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL34856 | 0.86 | MEN1 (0.68) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13041694 | 0.86 | MEN1 (0.68) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13287104 | 0.86 | MEN1 (0.68) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13041695 | 0.85 | RAB9A (0.64) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14193946 | 0.85 | NPC1 (0.74) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11931988 | 0.85 | NPC1 (0.74) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13533829 | 0.84 | NPBWR1 (0.58) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989037-B2 | A layer of discotic liquid-crystal and an anisotropic fluoropolymer of acrylic esters, e.g., 4-((4-nitrilophenoxy)butyl acrylate /2-(perfluorhexyl)ethyl acrylate copolymer; providing stability/optical compensation; no defects from optical fluctuation or alignment failure; controlling the tilt angle | FUJIFILM CORPORATION (JP) | 2011-08-02 | — | — | US | disclosed |
| US-20080090027-A1 | Composition, retardation plate, and liquid-crystal display device | FUJIFILM CORPORATION (JP) | 2008-04-17 | — | — | US | disclosed |