SCHEMBL13533829

SCHEMBL13533829

Cc1nc2cc(S(=O)(=O)c3ccc4nc(-c5ccc(C)c(C)c5)[nH]c4c3)ccc2[nH]1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPBWR1 P48145 3/20 0.58
MEN1 O00255 2/20 0.55
NPC1 O15118 2/20 0.55
POLB P06746 2/20 0.55
RAB9A P51151 2/20 0.55
KMT2A Q03164 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
GLA P06280 1/20 0.51
GAA P10253 1/20 0.51
MAPT P10636 1/20 0.51
GFER P55789 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51
CYP3A4 P08684 4/20 0.51
CYP2C9 P11712 4/20 0.51
CYP2C19 P33261 4/20 0.51
CYP1A2 P05177 3/20 0.51
SCD O00767 3/20 0.48
CYP2D6 P10635 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13533820 0.88 HSPD1 (0.57) NPBWR1MEN1NPC1POLBRAB9A
SCHEMBL13533810 0.85 NPBWR1 (0.58) NPBWR1MEN1NPC1POLBRAB9A
SCHEMBL13533825 0.84 NPC1 (0.54) NPBWR1MEN1NPC1POLBRAB9A
SCHEMBL12347958 0.84 NPC1 (0.68) NPBWR1MEN1NPC1POLBRAB9A
SCHEMBL13533840 0.81 NPC1 (0.71) NPBWR1MEN1NPC1POLBRAB9A
SCHEMBL26357467 0.81 MEN1 (0.56) NPBWR1MEN1NPC1POLBRAB9A
SCHEMBL12213875 0.80 NPBWR1 (0.54) NPBWR1MEN1NPC1POLBRAB9A
SCHEMBL13533794 0.80 NPC1 (0.60) NPBWR1MEN1NPC1POLBRAB9A
SCHEMBL13135752 0.79 HDAC6 (0.48) NPBWR1MEN1NPC1POLBRAB9A
SCHEMBL10330717 0.77 CHEK2 (0.51) NPBWR1MEN1NPC1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7649025-B2 Composite ion-exchange membrane TOYO BOSEKI KABUSHIKI KAISHA (JP) 2010-01-19 US disclosed
US-7537852-B2 Composite ion exchange membrane and electrolyte membrane electrode assembly TOYO BOSEKI KABUSHIKI KAISHA (JP) 2009-05-26 US disclosed