SCHEMBL12349376

SCHEMBL12349376

Cc1cnccc1N1c2ccccc2N(C)C1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 2/20 0.36
GAA P10253 1/20 0.36
ALOX12 P18054 1/20 0.36
PTPN2 P17706 1/20 0.36
PTPN1 P18031 1/20 0.36
TRPA1 O75762 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
FLT3 P36888 1/20 0.34
GSK3B P49841 1/20 0.34
GRM4 Q14833 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRL1 P41146 1/20 0.33
CYP1A2 P05177 2/20 0.33
CYP17A1 P05093 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
ATM Q13315 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17014635 1.00 KDM4E (0.36) KDM4EALDH1A1HPGDGAAALOX12
SCHEMBL11995096 0.89 ALDH1A1 (0.39) KDM4EALDH1A1HPGDGAAALOX12
SCHEMBL19258293 0.89 ALDH1A1 (0.39) KDM4EALDH1A1HPGDGAAALOX12
SCHEMBL23131266 0.89 ALDH1A1 (0.39) KDM4EALDH1A1HPGDGAAALOX12
SCHEMBL11995099 0.89 ALDH1A1 (0.39) KDM4EALDH1A1HPGDGAAALOX12
SCHEMBL17169564 0.87 FLT3 (0.37) KDM4EALDH1A1HPGDGAAALOX12
SCHEMBL17014632 0.87 FLT3 (0.37) KDM4EALDH1A1HPGDGAAALOX12
SCHEMBL11995104 0.83 ALDH1A1 (0.42) KDM4EALDH1A1HPGDGAAALOX12
SCHEMBL9891023 0.83 ALDH1A1 (0.42) KDM4EALDH1A1HPGDGAAALOX12
SCHEMBL12349380 0.83 ALDH1A1 (0.42) KDM4EALDH1A1HPGDGAAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11980086-B2 Use of transition metal carbene complexes in organic light-emitting diodes (OLEDs) UDC IRELAND LIMITED (IE) 2024-05-07 US disclosed
US-20240074302-A1 USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) UDC IRELAND LTD (IE) 2024-02-29 US disclosed
US-20140309428-A1 USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) BASF SE (DE) 2014-10-16 US disclosed
US-8384068-B2 Use of acridine derivatives as matrix materials and/or electron blockers in OLEDs BASF SE (DE) 2013-02-26 US disclosed
US-8373159-B2 Organic light-emitting diodes comprising carbene-transition metal complex emitter, and at least one compound selected from disilylcarbazoles, disilyldibenzofurans, disilyldibenzothiophenes, disilyldibenzophospholes, disilyldibenzothiophene s-oxides and disilyldibe BASF SE (DE) 2013-02-12 US disclosed
US-7989091-B2 Silanes containing phenothiazine-S-oxide or phenothiazine-S,S-dioxide groups and the use thereof in OLEDs BASF SE (DE) 2011-08-02 US disclosed
US-20100219403-A1 ORGANIC LIGHT-EMITTING DIODES COMPRISING CARBENE-TRANSITION METAL COMPLEX EMITTERS, AND AT LEAST ONE COMPOUND SELECTED FROM DISILYLCARBAZOLES, DISILYLDIBENZOFURANS, DISILYLDIBENZOTHIOPHENES, DISILYLDIBENZOPHOSPHOLES, DISILYLDIBENZOTHIOPHENE S-OXIDES AND DISILYLDIBENZOTHIOPHENE S,S-DIOXIDES BASF SE (DE) 2010-09-02 US disclosed
US-20100219406-A1 USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR ELECTRON BLOCKERS IN OLEDS BASF SE (DE) 2010-09-02 US disclosed
US-20100187980-A1 SILANES CONTAINING PHENOTHIAZINE-S-OXIDE OR PHENOTHIAZINE-S,S-DIOXIDE GROUPS AND THE USE THEREOF IN OLEDS BASF SE (DE) 2010-07-29 US disclosed
US-20080018238-A1 Use Of Phenothiazine-S-Oxides And Phenothiazine -S,S-Dioxides In The Form Of Matrix Materials For Organic Light-Emitting Diodes BASF AKTIENGESELLSCHAFT (DE) 2008-01-24 US disclosed
US-20080018221-A1 Use Of Transition Metal Carbene Complexes In Organic Light-Emitting Diodes (Oleds) BASF AKTIENGESELLSCHAFT (DE) 2008-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100187980-A1 SILANES CONTAINING PHENOTHIAZINE-S-OXIDE OR PHENOTHIAZINE-S,S-DIOXIDE GROUPS AND THE USE THEREOF IN OLEDS OPRD1, PPID, PLOD2 KDM4E 2722/4885ALDH1A1 980/4885HPGD 920/4885
US-11980086-B2 Use of transition metal carbene complexes in organic light-emitting diodes (OLEDs) OCIAD2, OCIAD1, ICOSLG KDM4E 4325/4885ALDH1A1 1981/4885HPGD 1454/4885
US-20080018221-A1 Use Of Transition Metal Carbene Complexes In Organic Light-Emitting Diodes (Oleds) OCIAD2, OCIAD1, ICOSLG KDM4E 4325/4885ALDH1A1 1981/4885HPGD 1454/4885
US-20100219403-A1 ORGANIC LIGHT-EMITTING DIODES COMPRISING CARBENE-TRANSITION METAL COMPLEX EMITTERS, AND AT LEAST ONE COMPOUND SELECTED FROM DISILYLCARBAZOLES, DISILYLDIBENZOFURANS, DISILYLDIBENZOTHIOPHENES, DISILYLDIBENZOPHOSPHOLES, DISILYLDIBENZOTHIOPHENE S-OXIDES AND DISILYLDIBENZOTHIOPHENE S,S-DIOXIDES DDT, GRIN2B, DRD1 KDM4E 3445/4885ALDH1A1 1149/4885HPGD 2360/4885
US-20240074302-A1 USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) OCIAD2, OCIAD1, ICOSLG KDM4E 4325/4885ALDH1A1 1981/4885HPGD 1454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.