Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13616969 | 0.94 | CETP (0.38) | CETPKCNH2IDO1SIGMAR1HSD11B1 | |
| SCHEMBL2584078 | 0.92 | IDO1 (0.47) | KCNH2IDO1SIGMAR1CHRM2HTR1A | |
| SCHEMBL12349721 | 0.86 | LTA4H (0.43) | IDO1ADRA1ASLC6A3TDP1L3MBTL1 | |
| SCHEMBL12713565 | 0.81 | KCNH2 (0.44) | CETPKCNH2IDO1SIGMAR1HSD11B1 | |
| SCHEMBL12349748 | 0.81 | LTA4H (0.39) | CETPIDO1ADRA1ASLC6A3TDP1 | |
| SCHEMBL18389767 | 0.81 | TDP1 (0.43) | KCNH2IDO1HPGDTDP1 | |
| SCHEMBL17232216 | 0.79 | SIGMAR1 (0.41) | IDO1SIGMAR1L3MBTL1 | |
| SCHEMBL18979042 | 0.78 | IDO1 (0.47) | KCNH2IDO1SIGMAR1CHRM2HTR1A | |
| SCHEMBL12349723 | 0.77 | IDO1 (0.38) | KCNH2IDO1SIGMAR1CHRM2HTR1A | |
| SCHEMBL12349736 | 0.77 | EBP (0.43) | SIGMAR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190467-A1 | Biological Polysiloxanes | VISION CRC LIMITED (AU) | 2011-08-04 | — | — | US | disclosed |