SCHEMBL2584078

SCHEMBL2584078

C[Si](C)(C)O[Si](C)(CCCc1ccccc1)O[Si](C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SIGMAR1 Q99720 4/20 0.41
MAOA P21397 1/20 0.41
CHRM2 P08172 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
CHRM1 P11229 1/20 0.40
DRD1 P21728 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
ADRA1A P35348 1/20 0.40
OPRM1 P35372 1/20 0.40
DRD3 P35462 1/20 0.40
SLC6A3 Q01959 1/20 0.40
KCNH2 Q12809 1/20 0.40
AOC3 Q16853 1/20 0.40
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12349777 0.92 CETP (0.42) IDO1L3MBTL1SIGMAR1CHRM2HTR1A
SCHEMBL12349721 0.90 LTA4H (0.43) IDO1L3MBTL1MEN1KMT2AADRA1A
SCHEMBL18389767 0.88 TDP1 (0.43) IDO1KCNH2AOC3HTR2A
SCHEMBL17232216 0.87 SIGMAR1 (0.41) IDO1L3MBTL1SIGMAR1MAOAMAOB
SCHEMBL13616969 0.86 CETP (0.38) IDO1L3MBTL1SIGMAR1CHRM2HTR1A
SCHEMBL12349748 0.85 LTA4H (0.39) IDO1KMT2AADRA1ASLC6A3
SCHEMBL18979042 0.85 IDO1 (0.47) IDO1L3MBTL1MEN1KMT2ASIGMAR1
SCHEMBL12349723 0.84 IDO1 (0.38) IDO1L3MBTL1MEN1KMT2ASIGMAR1
SCHEMBL1068905 0.82 IDO1 (0.44) IDO1L3MBTL1MEN1KMT2ASIGMAR1
SCHEMBL12349713 0.81 TDP1 (0.38) IDO1KCNH2AOC3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170166594-A1 Organosilicon modified photoinitiator and a photo-curable adhesive composition comprising the same HENKEL (CHINA) COMPANY LIMITED (CN) 2017-06-15 US disclosed
WO-2016029439-A1 ORGANOSILICON MODIFIED PHOTOINITIATOR AND PHOTO-CURABLE ADHESIVE COMPOSITION THEREOF HENKEL (CHINA) COMPANY LIMITED (CN) 2016-03-03 WO disclosed
US-8049024-B2 Heterogenized rhodium complexes, methods of their synthesis and application as hydrosilylation catalysts ADAM MICKIEWICZ UNIVERSITY (PL) 2011-11-01 US disclosed
US-20100048932-A1 New Heterogenized Rhodium Complexes, Methods of their Synthesis and Application as Hydrosilylation Catalysts ADAM MICKIEWICZ UNIVERSITY (PL) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048932-A1 New Heterogenized Rhodium Complexes, Methods of their Synthesis and Application as Hydrosilylation Catalysts SQLE, HAO2, IPO11 IDO1 79/4885L3MBTL1 4346/4885MEN1 2115/4885
US-20170166594-A1 Organosilicon modified photoinitiator and a photo-curable adhesive composition comprising the same ITGB2, ITGB8, C3AR1 IDO1 1193/4885L3MBTL1 332/4885MEN1 2329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.