SCHEMBL12350737

SCHEMBL12350737

CCCOC(=O)c1nnc(C)s1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.45
ALDH1A1 P00352 6/20 0.42
LMNA P02545 1/20 0.41
GRM6 O15303 1/20 0.40
ESR1 P03372 1/20 0.40
CHRM1 P11229 1/20 0.40
TSHR P16473 1/20 0.40
SLC6A2 P23975 1/20 0.40
KDR P35968 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
TP53 P04637 2/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
POLB P06746 2/20 0.36
AKT1 P31749 1/20 0.36
IRS1 P35568 1/20 0.36
GAB1 Q13480 1/20 0.36
GAA P10253 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12350733 0.90 TSHR (0.45) MAPTALDH1A1LMNAESR1TSHR
SCHEMBL12350752 0.88 TSHR (0.46) MAPTALDH1A1LMNAESR1TSHR
SCHEMBL4315953 0.87 ALDH1A1 (0.46) MAPTALDH1A1LMNATSHRTP53
SCHEMBL12350740 0.87 ALDH1A1 (0.47) MAPTALDH1A1LMNAESR1TSHR
SCHEMBL12350750 0.84 ALDH1A1 (0.46) MAPTALDH1A1LMNATSHRTP53
SCHEMBL12350743 0.83 RAB9A (0.34) MAPTALDH1A1LMNAESR1TSHR
SCHEMBL13800984 0.81 MAPT (0.44) MAPTALDH1A1LMNAGRM6ESR1
SCHEMBL12350756 0.80 L3MBTL1 (0.36) MAPTALDH1A1LMNATSHRTDP1
SCHEMBL12350757 0.79 SMN1; SMN2 (0.35) MAPTALDH1A1LMNATSHRTDP1
SCHEMBL12350766 0.78 ALDH1A1 (0.38) MAPTALDH1A1LMNATSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7989139-B2 Azo-metal chelate dye and optical recording medium MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) 2011-08-02 US disclosed
US-7989139-B2 Azo-metal chelate dye and optical recording medium MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) 2011-08-02 US disclosed
EP-1666538-B1 AZO METAL CHELATE COLORING MATTER AND OPTICAL RECORDING MEDIUM MITSUBISHI KAGAKU MEDIA CO LTD (JP) 2011-06-08 EP disclosed
US-20100098898-A1 AZO METAL CHELATE DYE AND OPTICAL RECORDING MEDIUM MITSUBISHI KAGAKU MEDIA CO., LTD (JP) 2010-04-22 US disclosed
US-20100098898-A1 AZO METAL CHELATE DYE AND OPTICAL RECORDING MEDIUM MITSUBISHI KAGAKU MEDIA CO., LTD (JP) 2010-04-22 US disclosed
US-7642036-B2 Azo-metal chelate dye and optical recording medium MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) 2010-01-05 US disclosed
US-7642036-B2 Azo-metal chelate dye and optical recording medium MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) 2010-01-05 US disclosed
US-20090246687-A1 AZO-METAL CHELATE DYE AND OPTICAL RECORDING MEDIUM MITSUBISHI KAGAKU MEDIA CO. LTD. (JP) 2009-10-01 US disclosed
US-20090246687-A1 AZO-METAL CHELATE DYE AND OPTICAL RECORDING MEDIUM MITSUBISHI KAGAKU MEDIA CO. LTD. (JP) 2009-10-01 US disclosed
EP-2070989-A1 METAL-CHELATE AZO DYE AND OPTICAL RECORDING MEDIUM Mitsubishi Kagaku Media Co., Ltd. (JP) 2009-06-17 EP disclosed