Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25969208 | 0.93 | ESR1 (0.64) | ESR1ESR2CA9CA12CA1 | |
| SCHEMBL12260131 | 0.90 | ALDH1A1 (0.51) | ESR1ESR2CA9CA12CA1 | |
| SCHEMBL1960350 | 0.88 | ALDH1A1 (0.50) | ESR1ESR2CA9CA12CA1 | |
| SCHEMBL26859786 | 0.88 | ESR1 (0.44) | ESR1ESR2CA9CA12CA1 | |
| SCHEMBL12360453 | 0.88 | ESR1 (0.54) | ESR1ESR2CA9CA12CA1 | |
| SCHEMBL24380215 | 0.87 | ESR1 (0.49) | ESR1CA9CA12CA1APP | |
| SCHEMBL1960124 | 0.85 | ALDH1A1 (0.47) | ESR1ESR2CA9CA12CA1 | |
| SCHEMBL19628661 | 0.85 | ALDH1A1 (0.47) | ESR1ESR2CA9CA12CA1 | |
| SCHEMBL4549126 | 0.85 | ALDH1A1 (0.47) | POLBAPPMEN1KMT2ANR1H3 | |
| SCHEMBL15494010 | 0.84 | CA9 (0.41) | ESR1ESR2CA9CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110188901-A1 | INTERMEDIATE TRANSFER MEMBER AND METHOD OF MANUFACTURE | XEROX CORPORATION (US) | 2011-08-04 | — | — | US | disclosed |
| US-20110143115-A1 | INTERMEDIATE TRANSFER MEMBER AND METHOD OF MANUFACTURE | XEROX CORPORATION (US) | 2011-06-16 | — | — | US | disclosed |