Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633304 | 0.82 | LMNA (0.55) | CYP1A2LMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL6154117 | 0.82 | LMNA (0.55) | CYP1A2LMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL633303 | 0.82 | LMNA (0.55) | CYP1A2LMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5070526 | 0.76 | MGLL (0.42) | MGLLALDH1A1GAAMEN1KMT2A | |
| SCHEMBL24819333 | 0.74 | ALDH1A1 (0.48) | LMNASMN1; SMN2ALDH1A1GAAALOX12 | |
| SCHEMBL13897189 | 0.72 | CYP1A2 (0.50) | CYP1A2LMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL19490270 | 0.71 | GAA (0.49) | CYP1A2LMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL12666945 | 0.71 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL24072582 | 0.71 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2ALDH1A1GAAHTT | |
| SCHEMBL591373 | 0.71 | LMNA (0.60) | LMNASMN1; SMN2ALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095311-A1 | POLYANIONIC MULTIVALENT MACROMOLECULES FOR INTRACELLULAR TARGETING OF PROLIFERATION AND PROTEIN SYNTHESIS | MIVENION GMBH (DE) | 2011-08-11 | — | — | WO | disclosed |