SCHEMBL1235504

SCHEMBL1235504

CC(F)(C(=O)NCCO)C(=O)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
POLB P06746 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CNR1 P21554 1/20 0.33
EPHX1 P07099 1/20 0.33
CA14 Q9ULX7 2/20 0.32
CA2 P00918 2/20 0.31
CA3 P07451 2/20 0.31
CA5A P35218 2/20 0.31
CA5B Q9Y2D0 2/20 0.31
CA1 P00915 1/20 0.31
CA12 O43570 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
USP2 O75604 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28890658 0.81 ALDH1A1 (0.64) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL1235502 0.81 ALDH1A1 (0.47) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL28026596 0.74 ALDH1A1 (0.60) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL14037588 0.74 ALDH1A1 (0.46) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL5463089 0.73 ALDH1A1 (0.44) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL733643 0.68 ALDH1A1 (0.68) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL3123112 0.68 ALDH1A1 (0.42) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL12565674 0.68 ALDH1A1 (0.42) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
SCHEMBL605200 0.68 POLB (0.46) ALDH1A1POLBSMN1; SMN2MEN1KMT2A
Methacrylic Acid SCHEMBL28394219 0.68 ALDH1A1 (0.49) ALDH1A1POLBSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2287270-B1 Compound containing a fluorinated amide group DU PONT (US) 2013-04-03 EP disclosed
US-8389657-B2 Poly(meth)acrylamides and poly(meth)acrylates containing flourinated amide E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-03-05 US disclosed
EP-2251363-B1 Poly(meth)acrylamides and poly(meth)acrylates containing fluorinated amide DU PONT (US) 2012-12-26 EP disclosed
US-20120264972-A1 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-10-18 US disclosed
EP-2054452-B1 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE DU PONT (US) 2012-09-19 EP disclosed
US-8178638-B2 Poly(meth)acrylamides and poly(meth)acrylates containing fluorinated amide E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-15 US disclosed
EP-2287270-A2 Composition containing fluorinated amide E. I. du Pont de Nemours and Company (US) 2011-02-23 EP disclosed
EP-2251363-A1 Poly(meth)acrylamides and poly(meth)acrylates containing fluorinated amide E. I. du Pont de Nemours and Company (US) 2010-11-17 EP disclosed
US-20100233419-A1 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE E.I.DU PONT DE NEMOURS AND COMPANY (US) 2010-09-16 US disclosed
US-7754838-B2 Poly(meth)acrylamides and poly(meth)acrylates containing fluorinated amide E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-13 US disclosed
EP-2054452-A2 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-06 EP disclosed
WO-2008021153-A2 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-02-21 WO disclosed
US-20080039605-A1 Poly(meth)acrylamides and poly(meth)acrylates containing fluorinated amide E. I. DU PONT DE NEMOURS AND COMPANY 2008-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100233419-A1 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE FGB, AFF1, AFF4 ALDH1A1 2720/4885POLB 535/4885SMN1; SMN2 1559/4885
US-20120264972-A1 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE AFF1, AFF2, AFF4 ALDH1A1 2429/4885POLB 528/4885SMN1; SMN2 1940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.