SCHEMBL733643

SCHEMBL733643

O=C(NCCO)C(F)(F)F

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
POLB P06746 1/20 0.68
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
CA3 P07451 2/20 0.58
CA5A P35218 2/20 0.58
CA5B Q9Y2D0 2/20 0.58
CA14 Q9ULX7 2/20 0.58
CA2 P00918 2/20 0.58
CA12 O43570 1/20 0.58
CA4 P22748 1/20 0.58
CA6 P23280 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
EPHX1 P07099 1/20 0.54
USP2 O75604 1/20 0.42
MAPT P10636 1/20 0.42
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6450550 0.86 CA3 (0.73) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL13861685 0.86 ALDH1A1 (0.79) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL865618 0.85 ALDH1A1 (0.77) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL864398 0.83 ALDH1A1 (0.82) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL21487547 0.82 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL14399469 0.82 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL3215133 0.81 MEN1 (0.83) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL2994990 0.81 MEN1 (0.83) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL712856 0.81 MEN1 (0.83) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL3221326 0.81 MEN1 (0.83) ALDH1A1SMN1; SMN2POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4725994-A1 COATING COMPOSITION FOR PREVENTING SEMICONDUCTOR PATTERN COLLAPSE, AND PATTERN COATED USING SAME Ycchem Co., Ltd. (KR) 2026-04-15 EP claimed
WO-2025018607-A1 COATING COMPOSITION FOR PREVENTING SEMICONDUCTOR PATTERN COLLAPSE, AND PATTERN COATED USING SAME 와이씨켐 주식회사 2025-01-23 WO claimed
CN-118725867-A High-selectivity uniform chip etching solution and preparation method and application thereof 浙江奥首材料科技有限公司 2024-10-01 CN claimed
CN-118516033-A Efficient demolding corrosion-resistant powder coating for building concrete templates 佛山市顺德区蓝天实业有限公司 2024-08-20 CN claimed
CN-116565327-A Use of fluorinated amide compounds for preparing electrolyte 西湖大学 2023-08-08 CN claimed
CN-112940245-A Biodegradable shrink film and preparation method thereof 湖州汇盎生物降解塑料制品有限公司 2021-06-11 CN claimed
EP-1926737-B1 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID DERIVATIVES HOFFMANN LA ROCHE (CH) 2017-03-15 EP claimed
CN-104151284-A Synthesis method and application of new methacrylamide orthoester monomer and acid-sensitive amphiphilic block copolymer thereof UNIV ANHUI 2014-11-19 CN claimed
EP-1951686-B1 QUINAZOLINE DERIVATIVES AS A MULTIPLEX INHIBITOR AND METHOD FOR THE PREPARATION THEREOF HANMI PHARM IND CO LTD (KR) 2013-04-03 EP claimed
EP-2038288-B1 NOVEL 4-AMINO-3-(-AZOLYL-PHENOXYMETHYL)-THIENOÝ3,2¨PYRIDINE-7-CARBOXYLIC ACID DERIVATIVES HOFFMANN LA ROCHE (CH) 2010-11-24 EP claimed
WO-2010040034-A2 METAL NANOPARTICLE INKS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2010-04-08 WO claimed
EP-2038288-A1 NOVEL 4-AMINO-3-(-AZOLYL-PHENOXYMETHYL)-THIENOÝ3,2¨PYRIDINE-7-CARBOXYLIC ACID DERIVATIVES F.HOFFMANN-LA ROCHE AG (CH) 2009-03-25 EP claimed
EP-1926737-A1 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID DERIVATIVES F.HOFFMANN-LA ROCHE AG (CH) 2008-06-04 EP claimed
US-20080009515-A1 Substituted thieno[3,2-C]pyridine carboxylic acid derivatives CHEN YI 2008-01-10 US claimed
WO-2008000697-A1 NOVEL 4-AMINO-3-(-AZOLYL-PHENOXYMETHYL)-THIENO[3,2]PYRIDINE-7-CARBOXYLIC ACID DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2008-01-03 WO claimed
WO-2007031428-A1 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2007-03-22 WO claimed
US-20070060607-A1 4-amino-thieno[3,2-c] pyridine-7-carboxylic acid derivatives BARTKOVITZ DAVID J 2007-03-15 US claimed
EP-0974557-B1 Method for forming article using sol-gel processing LUCENT TECHNOLOGIES INC (US) 2002-10-02 EP claimed
US-6209357-B1 AGING A SILICA DISPERSION WITH TETRAALKYLAMMONIUM HYDROXYDE STABILIZING AGENT,ADJUSTING THE ISOELECTRIC POINT TO9.0 OR HIGHER BY ADDING AMMONIUM HYDROXIDE OR AMINES;INDUCING GELATION AND DRYING;SILICA BODY OPTICAL FIBER PREFORM LUCENT TECHNOLOGIES INC. 2001-04-03 US claimed
EP-0974557-A1 Method for forming article using sol-gel processing LUCENT TECHNOLOGIES INC. (US) 2000-01-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070060607-A1 4-amino-thieno[3,2-c] pyridine-7-carboxylic acid derivatives BRAF, RAF1, MAP3K7 ALDH1A1 933/4885SMN1; SMN2 4134/4885POLB 3110/4885
US-20080009515-A1 Substituted thieno[3,2-C]pyridine carboxylic acid derivatives UQCRB, UQCRC2, AURKB ALDH1A1 379/4885SMN1; SMN2 4044/4885POLB 56/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.