SCHEMBL12355334

SCHEMBL12355334

C=CC(=O)NCc1c2ccccc2c(CNCc2ccccc2B(O)O)c2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 6/20 0.40
▸ KMT2A Q03164 3/20 0.34
▸ GAA P10253 1/20 0.34
▸ MEN1 O00255 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ EGFR P00533 1/20 0.33
▸ BTK Q06187 1/20 0.33
▸ CYP2C9 P11712 2/20 0.33
▸ LIPG Q9Y5X9 1/20 0.33
▸ ALDH1A1 P00352 3/20 0.32
▸ CYP2C19 P33261 2/20 0.32
▸ CYP3A4 P08684 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2245286 0.88 TGM2 (0.33) TGM2
SCHEMBL16634646 0.85 TGM2 (0.45) TGM2KMT2AGAACYP2C9LIPG
SCHEMBL232004 0.82 ZDHHC20 (0.40) TGM2CYP2C9LIPGALDH1A1CYP2C19
SCHEMBL12355335 0.78 TGM2 (0.32) TGM2
SCHEMBL12363839 0.76 — —
SCHEMBL14787896 0.74 CA12 (0.37) TGM2KMT2AGAACYP2C9ALDH1A1
SCHEMBL13970784 0.74 MC5R (0.40) KMT2AMEN1CYP2C9LIPGCYP2C19
SCHEMBL2245281 0.73 TGM2 (0.33) TGM2
SCHEMBL20346322 0.72 APP (0.32) KMT2AGAAMEN1CYP2C9LIPG
SCHEMBL12922751 0.71 ZDHHC20 (0.42) TGM2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8003397-B2 Glucose monitoring by viscometric sensing of polymeric fluid UNIVERSITY OF SOUTH CAROLINA (US) 2011-08-23 — — US disclosed
US-8003397-B2 Glucose monitoring by viscometric sensing of polymeric fluid UNIVERSITY OF SOUTH CAROLINA (US) 2011-08-23 — — US disclosed
US-20090191642-A1 Compositions, Systems, and Methods for Continuous Glucose Monitoring UNIVERSITY OF SOUTH CAROLINA (US) 2009-07-30 — — US disclosed
US-20090191642-A1 Compositions, Systems, and Methods for Continuous Glucose Monitoring UNIVERSITY OF SOUTH CAROLINA (US) 2009-07-30 — — US disclosed
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