SCHEMBL2245286

SCHEMBL2245286

C=CC(=O)NCc1c(C=CC)c(C=C)c(CNCc2ccccc2B(O)O)c2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 3/20 0.33
SLC2A1 P11166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12355334 0.88 TGM2 (0.40) TGM2
SCHEMBL2245281 0.84 TGM2 (0.33) TGM2
SCHEMBL2242039 0.81 EGFR (0.32)
SCHEMBL16634646 0.77 TGM2 (0.45) TGM2
SCHEMBL232004 0.74 ZDHHC20 (0.40) TGM2
SCHEMBL12355335 0.69 TGM2 (0.32) TGM2
SCHEMBL14787896 0.67 CA12 (0.37) TGM2
SCHEMBL12363839 0.67
SCHEMBL13970784 0.65 MC5R (0.40)
SCHEMBL12922751 0.65 ZDHHC20 (0.42) TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8003397-B2 Glucose monitoring by viscometric sensing of polymeric fluid UNIVERSITY OF SOUTH CAROLINA (US) 2011-08-23 US disclosed
US-20090191642-A1 Compositions, Systems, and Methods for Continuous Glucose Monitoring UNIVERSITY OF SOUTH CAROLINA (US) 2009-07-30 US disclosed