Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 8/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 4/20 | 0.31 |
| ▸ | RXRG | P48443 | 4/20 | 0.31 |
| ▸ | RARA | P10276 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12366086 | 0.88 | RXRA (0.40) | HSP90AA1RXRARARGPPARGRXRB | |
| SCHEMBL18651749 | 0.83 | POLB (0.40) | HSP90AA1GABRA1GABRB2RXRARARG | |
| SCHEMBL20312929 | 0.82 | GABRA1 (0.32) | HSP90AA1GABRA1GABRB2RXRARARG | |
| SCHEMBL14817161 | 0.81 | RARG (0.40) | HSP90AA1GABRA1GABRB2RXRARARG | |
| SCHEMBL23772217 | 0.76 | SRC (0.35) | HSP90AA1GABRA1GABRB2ALDH1A1MAPT | |
| SCHEMBL12355670 | 0.76 | CA1 (0.52) | KDM4EALDH1A1CYP1A2ALOX15SMN1; SMN2 | |
| SCHEMBL14452690 | 0.76 | HSP90AA1 (0.36) | HSP90AA1 | |
| SCHEMBL8028400 | 0.76 | CYP1A2 (0.35) | HSP90AA1RXRARXRBRXRGRARA | |
| SCHEMBL4018841 | 0.75 | HSP90AA1 (0.38) | HSP90AA1GABRA1GABRB2RXRARARG | |
| SCHEMBL23143159 | 0.73 | RXRA (0.50) | HSP90AA1RXRARARGPPARGRXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404902-B2 | Method for separating 1-butene from C4-containing hydrocarbon streams by hydroformylation | EVONIK OXENO GMBH (DE) | 2013-03-26 | — | — | US | disclosed |
| US-8003816-B2 | Bisphosphite ligands for hydroformylation catalyzed by transition metals | EVONIK OXENO GMBH (DE) | 2011-08-23 | — | — | US | disclosed |
| US-20110071321-A1 | METHOD FOR SEPERATING 1-BUTENE FROM C4-CONTAINING HYDROCARBON STREAMS BY HYDROFORMYLATION | EVONIK OXENO GMBH (DE) | 2011-03-24 | — | — | US | disclosed |
| US-20100036143-A1 | BISPHOSPHITE LIGANDS FOR HYDROFORMYLATION CATALYZED BY TRANSITION METALS | EVONIK OXENO GMBH (DE) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036143-A1 | BISPHOSPHITE LIGANDS FOR HYDROFORMYLATION CATALYZED BY TRANSITION METALS | SLC9B2, CTR9, POF1B | HSP90AA1 3045/4885GABRA1 2357/4885GABRB2 2458/4885 |
| US-20110071321-A1 | METHOD FOR SEPERATING 1-BUTENE FROM C4-CONTAINING HYDROCARBON STREAMS BY HYDROFORMYLATION | SLC9B2, INTS9, C9 | HSP90AA1 4016/4885GABRA1 1671/4885GABRB2 1282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.