Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 7/20 | 0.34 |
| ▸ | RXRB | P28702 | 5/20 | 0.34 |
| ▸ | RXRG | P48443 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12355667 | 0.76 | HSP90AA1 (0.38) | CYP1A2RXRARXRBRXRGALDH1A1 | |
| SCHEMBL14586980 | 0.71 | CYP1A2 (0.35) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL14817161 | 0.70 | RARG (0.40) | CYP3A4TSHRRXRAALDH1A1HSP90AA1 | |
| SCHEMBL30503395 | 0.70 | CYP1A2 (0.36) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL6899796 | 0.70 | CYP1A2 (0.35) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL11525106 | 0.70 | CYP1A2 (0.37) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL8028404 | 0.69 | RXRA (0.38) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL13626997 | 0.67 | LMNA (0.33) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL8026520 | 0.67 | MEN1 (0.47) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL23143159 | 0.67 | RXRA (0.50) | CYP3A4RXRARXRBRXRGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653431-B1 | Bis-(phosphinoalkoxy)-biaryl compounds and a process for preparing them | CELANESE CHEM EUROPE GMBH (DE) | 2000-03-01 | — | — | EP | disclosed |
| US-5498797-A | Bis(phosphinozlkoxy)biaryl compounds and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |
| EP-0653431-A1 | Bis-(phosphinoalkoxy)-biaryl compounds and a process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-17 | — | — | EP | disclosed |