Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2276943 | 0.90 | GAA (0.33) | ACHECES2TP53TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL37078 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL1236197 | 0.88 | ACHE (0.32) | ACHECES2TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL3278391 | 0.88 | ACHE (0.32) | ACHECES2 | |
| Hydrochloric Acid SCHEMBL1236569 | 0.86 | TAS1R3 (0.33) | ACHETAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL2274874 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL1236410 | 0.85 | HDAC3 (0.33) | ACHETAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL2276604 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL2870495 | 0.83 | NQO2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL142006 | 0.83 | NPC1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879960-B2 | methyl)(phenyl)methylene(3-tert-butyl-5-ethylcyclopentadienyl)(3,6-di-tert-butylfluorenyl)zirconium dichloride a metallocene], methylalumoxane, triisobutylaluminum containing catalyst system for propylene homo or copolymerization | MITSUI CHEMICALS, INC. (JP) | 2011-02-01 | — | — | US | disclosed |
| EP-1803742-B1 | PROCESS FOR PRODUCING PROPYLENE POLYMER | MITSUI CHEMICALS INC (JP) | 2010-06-23 | — | — | EP | disclosed |
| US-20080097055-A1 | Process for Producing Propylene Polymer | MITSUI CHEMICALS, INC. (JP) | 2008-04-24 | — | — | US | disclosed |
| EP-1803742-A1 | PROCESS FOR PRODUCING PROPYLENE POLYMER | Mitsui Chemicals, Inc. (JP) | 2007-07-04 | — | — | EP | disclosed |