Coumaric Acid

Coumaric Acid

SCHEMBL1235629

O=C(O)C=Cc1ccc(O)cc1.Oc1ccc2cc(Br)ccc2c1

nearest known ligand 0.64

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.64
AKR1B1 P15121 4/20 0.64
ESR2 Q92731 3/20 0.64
AKR1B10 O60218 3/20 0.64
TYR P14679 2/20 0.64
CA12 O43570 2/20 0.64
CA1 P00915 2/20 0.64
CA2 P00918 2/20 0.64
CA3 P07451 2/20 0.64
CA4 P22748 2/20 0.64
CA6 P23280 2/20 0.64
DPP4 P27487 2/20 0.64
CA5A P35218 2/20 0.64
CA7 P43166 2/20 0.64
CA9 Q16790 2/20 0.64
CA14 Q9ULX7 2/20 0.64
CA5B Q9Y2D0 2/20 0.64
PKM P14618 2/20 0.64
HCAR2 Q8TDS4 1/20 0.64
BACE1 P56817 5/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coumaric Acid SCHEMBL1235624 1.00 ESR1 (0.64) ESR1AKR1B1ESR2AKR1B10TYR
SCHEMBL26623498 0.85 AKR1C3 (0.57) ESR1AKR1B1ESR2AKR1B10TYR
SCHEMBL7692262 0.84 CA12 (0.66) ESR1AKR1B1ESR2AKR1B10TYR
SCHEMBL7692268 0.84 CA12 (0.66) ESR1AKR1B1ESR2AKR1B10TYR
SCHEMBL1235627 0.81 KMT2A (0.54) ESR1AKR1B1ESR2AKR1B10TYR
O-Coumaric Acid SCHEMBL5808585 0.80 NFKB1 (0.62) TYRCA1CA2CA4NFKB1
Coumaric Acid SCHEMBL39106 0.80 ESR1 (1.00) ESR1AKR1B1ESR2AKR1B10TYR
Coumaric Acid SCHEMBL6333097 0.80 ESR1 (1.00) ESR1AKR1B1ESR2AKR1B10TYR
Coumaric Acid SCHEMBL20702657 0.80 ESR1 (1.00) ESR1AKR1B1ESR2AKR1B10TYR
Coumaric Acid SCHEMBL43601 0.80 ESR1 (1.00) ESR1AKR1B1ESR2AKR1B10TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110152116-A1 NANOASSAYS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2011-06-23 US disclosed
US-7919019-B2 Nanostructure enhanced luminescent devices THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2011-04-05 US disclosed
US-7879575-B2 Tubes, rods from nylon; kits THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2011-02-01 US disclosed
US-20090246888-A1 NANOASSAYS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2009-10-01 US disclosed
US-20080286856-A1 Nanostructure Enhanced Luminescent Devices THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2008-11-20 US disclosed
US-20080193956-A1 Nanostructure Enhanced Luminescence THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2008-08-14 US disclosed
WO-2006116687-A2 NANOASSAYS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2006-11-02 WO disclosed
WO-2006116686-A2 NANOSTRUCTURE ENHANCED LUMINESCENT DEVICES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2006-11-02 WO disclosed
WO-2006116683-A1 NANOSTRUCTURE ENHANCED LUMINESCENCE THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2006-11-02 WO disclosed