SCHEMBL7692268

SCHEMBL7692268

O=C(O)C=Cc1ccc2cc(O)ccc2c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.66
CA1 P00915 3/20 0.66
CA2 P00918 3/20 0.66
CA3 P07451 3/20 0.66
CA4 P22748 3/20 0.66
CA6 P23280 3/20 0.66
CA5A P35218 3/20 0.66
CA7 P43166 3/20 0.66
CA9 Q16790 3/20 0.66
CA14 Q9ULX7 3/20 0.66
CA5B Q9Y2D0 3/20 0.66
HCAR2 Q8TDS4 3/20 0.66
AKR1B10 O60218 2/20 0.66
AKR1B1 P15121 2/20 0.66
DPP4 P27487 2/20 0.66
PKM P14618 2/20 0.66
TYR P14679 2/20 0.66
ESR1 P03372 1/20 0.66
ESR2 Q92731 1/20 0.66
KDM4E B2RXH2 5/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7692262 1.00 CA12 (0.66) CA12CA1CA2CA3CA4
SCHEMBL755207 0.90 KDM4E (0.64) CA12CA1CA2CA3CA4
SCHEMBL8746669 0.90 KDM4E (0.64) CA12CA1CA2CA3CA4
SCHEMBL11139376 0.84 KDM4E (0.62) CA12CA1CA2CA3CA4
SCHEMBL8746632 0.84 KDM4E (0.62) CA12CA1CA2CA3CA4
Coumaric Acid SCHEMBL1235624 0.84 ESR1 (0.64) CA12CA1CA2CA3CA4
Coumaric Acid SCHEMBL1235629 0.84 ESR1 (0.64) CA12CA1CA2CA3CA4
SCHEMBL9579426 0.84 PTGS1 (0.61) CA12CA1CA2CA3CA4
SCHEMBL78426 0.83 RELA (0.62) CA12CA1CA2CA3CA4
SCHEMBL6552210 0.83 RELA (0.62) CA12CA1CA2CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3816282-A1 ENZYMES OF LUCIFERIN BIOSYNTHESIS AND USE THEREOF Light Bio, Inc (US) 2021-05-05 EP disclosed
US-6335409-B1 LIQUID CRYSTAL ORIENTATION ROLIC AG (CH) 2002-01-01 US disclosed
US-6107427-A Cross-linkable, photoactive polymer materials ROLIC AG (CH) 2000-08-22 US disclosed