SCHEMBL1235869

SCHEMBL1235869

CCCCCCC(C)(C)c1cc(O)c2c(-c3cccc(C)c3)coc2n1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 17/20 0.44
CNR1 P21554 15/20 0.44
LTB4R Q15722 2/20 0.42
LTB4R2 Q9NPC1 2/20 0.42
ABCB1 P08183 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1264587 0.89 CNR1 (0.44) CNR2CNR1LTB4RLTB4R2
SCHEMBL1192791 0.85 LTB4R (0.41) CNR2CNR1LTB4RLTB4R2ABCB1
SCHEMBL1238204 0.82 CNR1 (0.39) CNR2CNR1
SCHEMBL1264702 0.80 CNR2 (0.45) CNR2CNR1
SCHEMBL1235880 0.80 CNR2 (0.37) CNR2CNR1
SCHEMBL2112954 0.78 CNR2 (0.51) CNR2CNR1LTB4RLTB4R2
SCHEMBL1264611 0.74 ABCB1 (0.40) CNR2CNR1ABCB1
SCHEMBL1192994 0.72 CNR1 (0.39) CNR2CNR1LTB4RLTB4R2
SCHEMBL1491148 0.70 CNR2 (0.48) CNR2CNR1LTB4RLTB4R2
SCHEMBL1236647 0.70 ABCB1 (0.52) CNR2CNR1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8431595-B2 Furanopyridine cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-04-30 US claimed
US-20110046176-A1 FURANOPYRIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2011-02-24 US claimed
WO-2011022692-A2 FURANOPYRIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) 2011-02-24 WO claimed
US-8431595-B2 Furanopyridine cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-04-30 US disclosed
US-8431595-B2 Furanopyridine cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-04-30 US disclosed
US-8431595-B2 Furanopyridine cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-04-30 US disclosed
US-20110046176-A1 FURANOPYRIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2011-02-24 US disclosed
US-20110046176-A1 FURANOPYRIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2011-02-24 US disclosed
US-20110046176-A1 FURANOPYRIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2011-02-24 US disclosed
WO-2011022692-A2 FURANOPYRIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) 2011-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046176-A1 FURANOPYRIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE CNR1, CNR2, FAAH CNR2 2/4885CNR1 1/4885LTB4R 208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.